Der Internist

, Volume 53, Issue 12, pp 1445–1455

Fieber ungeklärter Genese

Infektiöse Ursachen
  • B. Salzberger
  • A. Schneidewind
  • F. Hanses
  • G. Birkenfeld
  • M. Müller-Schilling
CME Zertifizierte Fortbildung


Infektionen sind mit einem Anteil von etwa 30% eine der häufigsten Ursachen eines ungeklärten Fiebers. Das Spektrum der Infektionen hängt von der klinischen Situation bzw. vom Risikoprofil des Patienten ab und variiert hinsichtlich der Kategorien des „klassischen“ Fiebers ungeklärter Genese und des ungeklärten Fiebers bei HIV-Infektion, bei immunsupprimierten Patienten und bei nosokomialem Fieber. Die wichtigste Frage ist, welche Eigenschaften von Erreger und Wirt eine spezifische Infektion zur Ursache eines ungeklärten Fiebers machen können.


Fieber ungeklärter Genese Fieber unbekannter Genese HIV-Infektionen Immunsuppression Immunrekonstitutionssyndrom 

Fever of unknown origin

Infectious causes


Infectious diseases remain one of the most important causes of fever of unexplained origin (FUO). We review the spectrum of infectious diseases in the different clinical situations of patients with FUO, namely in classical FUO, in patients with HIV infection, in health care-associated or nosocomial FUO, and in immunocompromised patients with FUO. The most important question is which clinical features make a specific disease a candidate to cause FUO.


Fever of unexplained origin Fever of unknown origin HIV infections Immunosuppression Immune reconstitution inflammatory syndrome 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • B. Salzberger
    • 1
  • A. Schneidewind
    • 1
  • F. Hanses
    • 1
  • G. Birkenfeld
    • 1
  • M. Müller-Schilling
    • 1
  1. 1.Klinik und Poliklinik für Innere Medizin IUniversitätsklinikum RegensburgRegensburgDeutschland

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