Fieber und erniedrigte CD4-Zellzahl bei einem 22-jährigen Patienten aus Ghana
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Zusammenfassung
Ein 22-jähriger Patient aus Ghana ohne relevante Komorbiditäten wurde 2-malig bei unklarem Fieber und erniedrigter CD4-Zellzahl hospitalisiert. Beim zweiten stationären Aufenthalt konnte nach verlängerter Bebrütungsdauer der Blutkulturen und Nachweis von Vegetationen im transösophagealen Echokardiogramm eine Mitralklappenendokarditis durch Aggregatibacter aphrophilus diagnostiziert werden. Die entsprechend den Leitlinien über 4 Wochen durchgeführte Therapie führte zur Entfieberung, Auflösung der Vegetationen und zum Wiederanstieg der CD4-Zellzahl.
Schlüsselwörter
Endokarditis Fieber unklarer Genese Blutkulturen CD4-Lymphozytenzahl Transösophageale EchokardiographieA 22-year-old patient from Ghana with fever and reduced CD4 T-cell count
Abstract
A 22-year-old patient from Ghana without relevant co-morbidities was admitted twice with fever of unknown origin and reduced CD4 T-cell count. During the second hospital stay, after prolonged incubation of blood cultures and detection of vegetations on the mitral valve in a transesophageal echocardiogram, infectious endocarditis with Aggregatibacter aphrophilus was diagnosed. Treatment according to European guidelines resulted in resolution of the fever, dissolution of the mitral valve vegetations and recovery of CD4 T-cell count.
Keywords
Endocarditis Fever of unknown origin Blood cultures CD4 lymphocyte count Echocardiography, transesophagealNotes
Danksagung
Diese Arbeit wurde durch das Bundesministerium für Bildung und Forschung (BMBF) gefördert (Förderkennzeichen: 01EO1002 und 01KI1204).
Interessenkonflikt
Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht.
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