Der Internist

, Volume 49, Issue 8, pp 999–1001

Hydrokortison in der Sepsis

Ein physiologisches Konzept ohne Wirkung?
Klinische Studien
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Hydrocortisone in sepsis

A physiological concept without effect?

Literatur

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    Annane D, Sebille V, Charpentier C et al. (2002) Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288: 871CrossRefGoogle Scholar
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    Annane D, Bellissant E, Bolleart PE et al. (2004) Corticosteroides for severe sepsis and septic shock: a systematic review and meta analysis. BMJ 329: 480–488PubMedCrossRefGoogle Scholar
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    Bellisant EAD (2000) Effect of hydrocortisone on phenylephrine-mean arterial pressure dose respone relationship in septic shock. Clin Pharmacol Ther 68: 293–303CrossRefGoogle Scholar
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    Hafezi-Moghadam A, Simoncini T, Yang Z et al. (2002) Acute cardiovascular protective effects of corticosteroids are mediated by non transcriptional activation of endothelial nitric oxide sythetase. Nat Med 8: 473–479PubMedCrossRefGoogle Scholar
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Copyright information

© Springer Medizin Verlag 2008

Authors and Affiliations

  1. 1.StuttgartStuttgartDeutschland
  2. 2.Klinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Carl Gustav CarusMedizinische Fakultät, Technischen Universität DresdenDresdenDeutschland

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