HNO

, Volume 54, Issue 11, pp 833–841 | Cite as

Diagnostik und Therapie der auditorischen Synaptopathie/Neuropathie

  • T. Moser
  • N. Strenzke
  • A. Meyer
  • A. Lesinski-Schiedat
  • T. Lenarz
  • D. Beutner
  • A. Foerst
  • R. Lang-Roth
  • H. von Wedel
  • M. Walger
  • M. Gross
  • A. Keilmann
  • A. Limberger
  • T. Steffens
  • J. Strutz
Leitthema

Zusammenfassung

Die audiologische Konstellation von pathologischen frühen akustisch evozierten Potenzialen (fehlend, erhöhte Schwelle und gestörte Kurvenform) trotz nachweisbarer otoakustischer Emissionen geht häufig mit einer von schlechtem Sprachverständnis geprägten Schwerhörigkeit bzw. mit Taubheit einher. Diese als auditorische Neuropathie erstbeschriebene, heterogene Erkrankungsgruppe beinhaltet peripher-auditorische Störungen der synaptischen Schallkodierung durch innere Haarzellen (Synaptopathie) und/oder der Erregungsbildung und -weiterleitung im Hörnerv (Neuropathie). Dieses Konsensuspapier gibt aktuelle Hintergrundinformationen sowie Empfehlungen zur Diagnostik und Therapie im deutschsprachigen Raum. Es nimmt dabei Bezug auf aktuelle internationale Statements.

Schlüsselwörter

Synaptopathie Neuropathie Taubheit Sprachverständnis 

Diagnosis and therapy of auditory synaptopathy/neuropathy

Abstract

Pathological auditory brainstem responses (lack of responses, elevated thresholds and perturbed waveforms) in combination with present otoacoustic emissions are typical audiometric findings in patients with a hearing impairment that particularly affects speech comprehension or complete deafness. This heterogenous group of disorders first described as “auditory neuropathy” includes dysfunction of peripheral synaptic coding of sound by inner hair cells (synaptopathy) and/or of the generation and propagation of action potentials in the auditory nerve (neuropathy). This joint statement provides prevailing background information as well as recommendations on diagnosis and treatment. The statement focuses on the handling in the german language area but also refers to current international statements.

Keywords

Synaptopathy Neuropathy Deafness Speech recognition 

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Copyright information

© Springer Medizin Verlag 2006

Authors and Affiliations

  • T. Moser
    • 1
  • N. Strenzke
    • 1
  • A. Meyer
    • 1
  • A. Lesinski-Schiedat
    • 2
  • T. Lenarz
    • 2
  • D. Beutner
    • 3
  • A. Foerst
    • 3
  • R. Lang-Roth
    • 3
  • H. von Wedel
    • 3
  • M. Walger
    • 3
  • M. Gross
    • 4
  • A. Keilmann
    • 5
  • A. Limberger
    • 5
  • T. Steffens
    • 6
  • J. Strutz
    • 6
  1. 1.HNO-Universitätsklinik GöttingenGöttingenGermany
  2. 2.HNO-KlinikMedizinische Hochschule HannoverGermany
  3. 3.HNO-Universitätsklinik KölnGermany
  4. 4.Klinik für Audiologie und PhoniatrieCharité – Universitätsmedizin BerlinGermany
  5. 5.Univ.-Klinik für Kommunikationsstörungen MainzGermany
  6. 6.HNO-Universitätsklinik RegensburgGermany

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