Skip to main content
Log in

Schlafmangel und Insomnie

Einfluss auf die körperliche und psychische Gesundheit

Lack of sleep and insomnia

Impact on somatic and mental health

  • Leitthema
  • Published:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

Zusammenfassung

Die Begriffe „Schlafmangel“ und „Insomnie“ sollten nicht synonym verwendet und nicht verwechselt werden. Als Schlafmangel wird eine Verkürzung der üblichen Schlafdauer eines Menschen bezeichnet, die durch äußere Umstände oder motivationale Faktoren bedingt ist. Bei einer Insomnie liegt hingegen eine für die Betroffenen nicht erklärbare und mit einem Leidensdruck verbundene Störung des Schlafs vor, obwohl die äußeren Umstände nicht gegen einen ausreichend langen Schlaf sprechen. Die meisten Studien zum Thema Schlafmangel untersuchten den Zusammenhang zwischen der Schlafdauer sowie körperlicher und psychischer Gesundheit. Die Längsschnittstudien zeigten dabei, dass Menschen mit einer verkürzten Schlafdauer (< 6 Stunden) ein erhöhtes Risiko für das Auftreten eines metabolischen Syndroms und für kardiovaskuläre Erkrankungen aufweisen. Zudem zeigte sich ein U-förmiger Zusammenhang zwischen der Schlafdauer und Mortalität, das heißt, die Mortalität ist sowohl bei einer verkürzten (< 6 Stunden) als auch bei einer verlängerten Schlafdauer (> 8 Stunden) erhöht. In Bezug auf Insomnien konnten ähnliche, allerdings schwächer ausgeprägte Zusammenhänge gezeigt werden. Zudem sind Insomnien Risikofaktoren für psychische Erkrankungen, insbesondere für Depressionen. Die Befunde legen nahe, dem Thema Schlaf und Schlafstörungen in der ärztlichen Praxis mehr Zeit einzuräumen und diesbezügliche Präventionsmaßnahmen zu stärken.

Abstract

Lack of sleep and insomnia need to be viewed differently. Lack of sleep implies a shortening of the habitual sleep duration due to external circumstances or motivational factors. Insomnia, in contrast, is defined as a sleep disorder due to unknown reasons for the afflicted subjects. People with insomnia suffer from being unable to sleep, in spite of adequate external circumstances. Research on lack of sleep/shortened sleep duration has focused on relationships with somatic and mental health. Longitudinal studies revealed that a shortening of sleep duration (< 6 h) is associated with an increased risk for the metabolic syndrome and cardiovascular diseases. For sleep duration and mortality, a U-shaped relationship was found, indicating that both shortened (< 6 h) and prolonged sleep durations (> 8 h) are associated with increased mortality. Similar, albeit weaker, correlations were described for insomnia and somatic health. In addition, insomnia is a risk factor for the development of mental disorders, especially depression. These relationships suggest that the area of sleep and sleep disorders should be integrated into everyday medical practice and that preventive approaches to somatic and mental disorders should encompass the topic of sleep to a much stronger extent than currently practiced.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1

Literatur

  1. Edinger JD, Bonnet MH, Bootzin RR et al (2004) Derivation of research diagnostic criteria for insomnia: report of an American academy of sleep medicine work group. Sleep 27:1567–1596

    PubMed  Google Scholar 

  2. Peter H, Penzel T, Peter JH (2007) Enzyklopädie der Schlafmedizin. Springer, Berlin

  3. AASM (2005) International classification of sleep disorder, 2. Aufl. Westchester, Illinios

  4. Horne J (1988) Why we sleep. Oxford University Press, Oxford

  5. Van Dongen HP, Maislin G, Mullington JM, Dinges DF (2003) The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep 26:117–126

    Google Scholar 

  6. American Psychiatric Association (1994) Diagnostic and statistical manual, 4. Aufl. American Psychiatric Association, Washington D.C

  7. NIH, National Institutes of Health State of the Science Conference Statement (2005) Manifestations and management of chronic insomnia in adults, June 13–15. Sleep 28:1049–1057

    Google Scholar 

  8. Reynolds CF, Redline S, Morin C et al (2010) The DSM-V sleep-wake disorders nosology: an update and an invitation to the sleep community. Sleep 33:10–11

    PubMed  Google Scholar 

  9. Ohayon M (2002) Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev 6:97–111

    Article  PubMed  Google Scholar 

  10. Riemann D, Hajak G (2009) Insomnien: I. Ätiologie, Pathophysiologie und Diagnostik. Nervenarzt 9:1060–1069

    Article  Google Scholar 

  11. Spiegelhalder K, Scholtes C, Riemann D (2010) The association between insomnia and cardiovascular diseases. Nature Sci Sleep 2:71–78

    Article  Google Scholar 

  12. Haynes SN, Adams A, Franzen M (1981) The effects of presleep stress on sleep-onset insomnia. J Abnorm Psychol 90:601–606

    Article  PubMed  CAS  Google Scholar 

  13. Bonnet MH, Arand DL (1998b) Heart rate variability in insomniacs and matched normal sleepers. Psychosom Med 60:610–615

    PubMed  CAS  Google Scholar 

  14. Fox K, Borer JS, Camm AJ et al (2007) Resting heart rate in cardiovascular disease. J Am Coll Cardiol 50:823–830

    Article  PubMed  Google Scholar 

  15. Lahiri MK, Kannankeril PJ, Goldberger JJ (2008) Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic implications. J Am Coll Cardiol 51:1725–1733

    Article  PubMed  Google Scholar 

  16. Nilsson PM, Nilsson JA, Hedblad B, Berglund G (2001) Sleep disturbance in association with elevated pulse rate for prediction of mortality – consequences of mental strain? J Intern Med 250:521–529

    Article  PubMed  CAS  Google Scholar 

  17. Jurysta F, Lanquart JP, Sputaels V et al (2009) The impact of chronic primary insomnia on the heart rate – EEG variability link. Clin Neurophysiol 120:1054–1060

    Article  PubMed  CAS  Google Scholar 

  18. Spiegelhalder K, Fuchs L, Ladwig J et al (2011) Heart rate and heart rate variability in subjectively reported insomnia. J Sleep Res 20:137–145

    Article  PubMed  Google Scholar 

  19. Ben-Dov IZ, Kark JD, Ben-Ishay D et al (2007) Blunted heart rate dip during sleep and all-cause mortality. Arch Intern Med 167:2116–2121

    Article  PubMed  Google Scholar 

  20. Gangwisch JE, Heymsfield SB, Boden-Albala B et al (2006) Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey. Hypertension 47:833–839

    Article  PubMed  CAS  Google Scholar 

  21. Suka M, Yoshida K, Sugimori H (2003) Persistent insomnia is a predictor of hypertension in Japanese male workers. J Occup Health 45:344–350

    Article  PubMed  Google Scholar 

  22. Knutson KL, Van Cauter E, Rathouz PJ et al (2009) Association between sleep and blood pressure in midlife: the CARDIA sleep study. Arch Intern Med 169:1055–1061

    Article  PubMed  Google Scholar 

  23. Phillips B, Mannino DM (2007) Do insomnia complaints cause hypertension or cardiovascular disease? J Clin Sleep Med 3:489–494

    PubMed  Google Scholar 

  24. Phillips B, Buzkova P, Enright P (2009) Insomnia did not predict incident hypertension in older adults in the cardiovascular health study. Sleep 32:65–72

    PubMed  Google Scholar 

  25. Vgontzas AN, Liao D, Bixler EO et al (2009) Insomnia with objective short sleep duration is associated with a high risk for hypertension. Sleep 32:491–497

    PubMed  Google Scholar 

  26. Lanfranchi PA, Pennestri MH, Fradette L et al (2009) Night time blood pressure in normotensive subjects with chronic insomnia: implications for cardiovascular risk. Sleep 32:760–766

    PubMed  Google Scholar 

  27. Schwartz SW, Cornoni-Huntley J, Cole SR et al (1998) Are sleep complaints an independent risk factor for myocardial infarction? Ann Epidemiol 8:384–392

    Article  PubMed  CAS  Google Scholar 

  28. Mallon L, Broman JE, Hetta J (2002) Sleep complaints predict coronary artery disease mortality in males: a 12-year follow-up study of a middle-aged Swedish population. J Intern Med 251:207–216

    Article  PubMed  CAS  Google Scholar 

  29. Schwartz S, Anderson WM, Cole SR et al (1999) Insomnia and heart disease: a review of epidemiologic studies. J Psychosom Res 47:313–333

    Article  PubMed  CAS  Google Scholar 

  30. Kripke DF, Garfinkel L, Wingard DL et al (2002) Mortality associated with sleep duration and insomnia. Arch Gen Psychiat 59:131–136

    Article  PubMed  Google Scholar 

  31. Gallicchio L, Kalesan B (2009) Sleep duration and mortality: a systematic review and meta-analysis. J Sleep Res 18:148–158

    Article  PubMed  Google Scholar 

  32. Grandner MA, Hale L, Moore M, Patel NP (2010) Mortality associated with short sleep duration: the evidence, the possible mechanisms and the future. Sleep Med Rev 14:191–203

    Article  PubMed  Google Scholar 

  33. Vgontzas A, Liao D, Pejovic S et al (2010) Insomnia with short sleep duration and mortality: the Penn state cohort. Sleep 33:1159–1164

    PubMed  Google Scholar 

  34. Vorona R, Winn MP, Babineau TW et al (2005) Overweight and obese patients in a primary care population report less sleep than patients with a normal body mass index. Arch Intern Med 165:25–30

    Article  PubMed  Google Scholar 

  35. Bass J, Turek FW (2005) Sleepless in America – a pathway to obesity and the metabolic syndrome? Arch Intern Med 165:15–16

    Article  PubMed  Google Scholar 

  36. Patel S, Hu FB (2008) Short sleep duration and weight gain: a systematic review. Obesity 16:643–653

    Article  PubMed  Google Scholar 

  37. Chen X, Beydoun MA, Wang Y (2008) Is sleep duration associated with childhood obesity? A systematic review and meta-analysis. Obesity 16:265–274

    Article  PubMed  Google Scholar 

  38. Marshall NS, Glozier N, Grunstein RR (2008) Is sleep duration related to obesity? A critical review of the epidemiological evidence. Sleep Med Rev 12:289–298

    Article  PubMed  Google Scholar 

  39. Nielsen LS, Danielsen KV, Sorensen TI (2011) Short sleep duration as a possible cause of obesity: critical analysis of the epidemiological evidence. Obes Rev 12:78–92

    Article  PubMed  CAS  Google Scholar 

  40. Nilsson PM, Röst M, Engström G et al (2004) Incidence of diabetes in middle-aged men is related to sleep disturbances. Diabetes Care 27:2464–2469

    Article  PubMed  Google Scholar 

  41. Mallon L, Broman JE, Hetta J (2005) High incidence of diabetes in men with sleep complaints or short sleep duration. Diabetes Care 28:2762–2767

    Article  PubMed  Google Scholar 

  42. Hayashino Y, Fukuhara S, Suzukamo Y et al (2007) Relation between sleep quality and quantity, quality of life, and risk of developing diabetes in healthy workers in Japan: the high risk and population strategy for occupational health promotion. BMC Public Health 7:129–137

    Article  PubMed  Google Scholar 

  43. Vgontzas AN, Liao D, Pejovic S et al (2009) Insomnia with objective short sleep duration is associated with type 2 diabetes: a population-based study. Diabetes Care 32:1980–1985

    Article  PubMed  Google Scholar 

  44. Spiegel K, Leproult R, Cauter E van (1999) Impact of sleep debt on metabolic and endocrine function. Lancet 354:1435–1439

    Article  PubMed  CAS  Google Scholar 

  45. Spiegel K, Tasali E, Leproult R, Cauter E van (2009) Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocr 5:253–261

    Article  CAS  Google Scholar 

  46. Riemann D, Berger M, Voderholzer U (2001) Sleep and depression – results from psychobiological studies: an overview. Biol Psychol 57:67–103

    Article  PubMed  CAS  Google Scholar 

  47. Ford DE, Kamerow DB (1989) Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA 262:1479–1484

    Article  PubMed  CAS  Google Scholar 

  48. Riemann D, Voderholzer U (2003) Primary insomnia: a risk factor to develop depression? J Affect Disord 76:255–259

    Article  PubMed  Google Scholar 

  49. Baglioni C, Battagliese G, Feige B et al (im Druck) Insomnia is a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord

  50. Riemann D, Perlis ML (2009) The treatments of chronic insomnia: a review of benzo-diazepine receptor agonists and psychological and behavioural therapies. Sleep Med Rev 13:205–214

    Article  PubMed  Google Scholar 

  51. Riemann D, Spiegelhalder K, Feige B et al (2010) The hyperarousal concept of insomnia: a review of the concept and its evidence. Sleep Med Rev 14:19–31

    Article  PubMed  Google Scholar 

Download references

Danksagung

Aktuelle Forschungsarbeiten von D. Riemann, K. Spiegelhalder und C. Baglioni zum Thema dieses Artikels werden mit EU-Mitteln gefördert (OPTIMI, GAN 248544; Marie Curie IEF, GAN 235231).

Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehungen hin: D. Riemann hat im letzten Jahr Mittel zur Durchführung einer „Investigator Initiated Study“ von Sanofi Aventis bekommen. Die beiden anderen Autoren geben keinen Interessenkonflikt an.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to D. Riemann.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Riemann, D., Baglioni, C. & Spiegelhalder, K. Schlafmangel und Insomnie. Bundesgesundheitsbl. 54, 1296–1302 (2011). https://doi.org/10.1007/s00103-011-1378-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00103-011-1378-y

Schlüsselwörter

Keywords

Navigation