Schmerztherapie und symptomorientierte Behandlung in der Palliativmedizin

Leitthema: Palliative Versorgung in Deutschland

Zusammenfassung

Belastende körperliche Beschwerden, insbesondere starke Schmerzen, bedeuten für viele Patienten mit fortgeschrittener Erkrankung eine wesentliche Einschränkung ihrer Lebensqualität. Bei der symptomorientierten Behandlung von Patienten mit unheilbaren Erkrankungen sollten ihre Bedürfnisse und Wünsche im Mittelpunkt stehen und möglichst wenig invasive Therapieoptionen gewählt werden. Dieser Übersichtartikel vermittelt die Grundlagen zur Behandlung der wichtigsten Symptome in der Palliativmedizin, die sich an den Richtlinien der Weltgesundheitsorganisation (WHO) orientieren.

Schlüsselwörter

Symptomorientierte Behandlung Schmerztherapie Palliativmedizin Opioide WHO 

Pain and symptom management in palliative care

Abstract

Physical complaints, especially severe pain, result in a massive restriction of a patient’s quality of life, especially in the late stages of their disease. The patient’s needs and wishes should be the primary goal of any symptom-aimed therapeutic measure. Before initiating or continuing any antineoplastic procedure (e.g., radiation, chemotherapy), it is essential to thoroughly consider their benefits and side effects, since some patients benefit considerably more from quality of life oriented symptom control. This review article describes the basics of cancer pain therapy and symptom management, which are based on the guidelines published by the World Health Organization (WHO).

Keywords

symptom management pain dyspnoe palliative care opioids WHO 

Literatur

  1. 1.
    Nauck F, Radbruch L, Ostgathe C et al. (2002) Kerndokumentation für Palliativstationen -Strukturqualität und Ergebnisqualität. Palliativmedizin 3:41-9CrossRefGoogle Scholar
  2. 2.
    World Health Organisation (1998) Symptom relief in terminal illness. Eigenverlag, GenevaGoogle Scholar
  3. 3.
    Hanks GW, Conno F, Cherny N et al. (2001) Morphine and alternative opioids in cancer pain: the EAPC recommendations. Br J Cancer 84:587-93CrossRefPubMedGoogle Scholar
  4. 4.
    Nauck F, Ostgathe C, Klaschik E et al. (2004) Drugs in palliative care: results from a representative survey in Germany. Palliat Med 18:100-07CrossRefPubMedGoogle Scholar
  5. 5.
    Nauck F, Radbruch L (2006) Medikamentöse Schmerztherapie. In: Aulbert E, Radbruch L, Nauch F (Hrsg) Lehrbuch der Palliativmedizin, 3. Aufl. Schattauer, Stuttgart New YorkGoogle Scholar
  6. 6.
    Zenz M, Jurna I (2001) Lehrbuch der Schmerztherapie, 2. Aufl. Wissenschaftliche Verlagsgesellschaft, StuttgartGoogle Scholar
  7. 7.
    Cherny N, Ripamonti C, Pereira J et al. (2001) Strategies to manage the adverse effects of oral morphine: an evidence-based report. J Clin Oncol 19:2542-554PubMedGoogle Scholar
  8. 8.
    Radbruch L, Nauck F, Sabatowski R (2002) Germany. Cancer pain and palliative care -current situation. J Pain Symptom Manage 24:183-87CrossRefPubMedGoogle Scholar
  9. 9.
    Mercadante S, Radbruch L, Caraceni A et al. (2002) Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care. Cancer 94(3):832-39CrossRefPubMedGoogle Scholar
  10. 10.
    Todd J, Rees E, Gwilliam B et al. (2002) An assessment of the efficacy and tolerability of a „double dose-of normal-release morphine sulphate at bedtime. Palliat Med 16:507-12CrossRefPubMedGoogle Scholar
  11. 11.
    Elsner F, Radbruch L, Joick G et al. (2005) Intravenous versus subcutaneous morphine titration in patients with persisting exacerbation of cancer pain. J Palliat Med 8:743-50CrossRefPubMedGoogle Scholar
  12. 12.
    Bruera E, Sweeney K, Willey J et al. (2003) A randomized controlled trial of supplemental oxygen versus air in cancer patients with dyspnea. Palliat Med 17:659-63PubMedGoogle Scholar
  13. 13.
    Driver L, Bruera E (2002) Dyspnea. In: The M.D. Anderson Palliative Care Handbook, 2nd edn. The University of Texas. Health Science Printing, Houston, pp 71-6Google Scholar
  14. 14.
    Nauck F (2001) Symptom control in the terminal phase. Schmerz 15:362-69CrossRefPubMedGoogle Scholar
  15. 15.
    Vietta L, Kenner D, Sali A (2000) Bacterial infections in terminally ill hospice patients. J Pain Symptom Manage 20:326-34CrossRefGoogle Scholar
  16. 16.
    Friedlander MM, Brayman Y, Breitbart WS (2004) Delirium in palliative care. Oncology 18:1541-550PubMedGoogle Scholar
  17. 17.
    Vella-Brincat J, Macleod AD (2004) Haloperidol in palliative care. Palliat Med 18:195-01CrossRefPubMedGoogle Scholar
  18. 18.
    Caraceni A, Bosisio M (2004) Acute confusional state. In: Voltz R et al. (eds) Palliative care in neurology. Oxford University Press, Oxford New York, pp 228-40Google Scholar
  19. 19.
    Ahmedzai S (1998) Palliation of respiratory symptoms. In: Doyle D, Hanks GWC, MacDonald N (eds) Oxford textbook of palliat Med, 2nd edn. Oxford University Press, Oxford New York, pp 583-16Google Scholar
  20. 20.
    Radbruch L, Nauck F, Fuchs M et al. (2002). What is palliative care in Germany? Results from a representative survey. J Pain Symptom Manage 23(6):471-83CrossRefPubMedGoogle Scholar
  21. 21.
    Nauck F, Ostgathe C, Dickerson ED (2001) A German model for methadone conversion. Am J Hosp Palliat Care 18(3):200-02CrossRefPubMedGoogle Scholar

Copyright information

© Springer Medizin Verlag 2006

Authors and Affiliations

  1. 1.Universitätsklinikum KölnKlinik und Poliklinik für PalliativmedizinKölnBRD
  2. 2.Universitätsklinikum KölnKlinik und Poliklinik für PalliativmedizinKölnBRD

Personalised recommendations