Die Variante der Creutzfeldt-Jakob-Krankheit (vCJK)

Epidemiologie, Erkennung, Diagnostik und Prävention unter besonderer Berücksichtigung der Risikominimierung einer iatrogenen Übertragung durch Medizinprodukte, insbesondere chirurgische Instrumente — Abschlussbericht der Task Force vCJK zu diesem Thema
Mitteilung

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Hörnlimann B, Riesner D, Kretzschmar H (2001) Prionen und Prionkrankheiten. Walter de Gruyter, Berlin New YorkGoogle Scholar
  2. 2.
    Prusiner SB (2001) Shattuck lecture — neurodegenerative diseases and prions. N Engl J Med 344:1516–1526PubMedCrossRefGoogle Scholar
  3. 3.
    Brown P, Preece JP, Brandel T et al. (2000) Iatrogenic Creutzfeldt-Jakob disease at the millenium. Neurology 55:1075–1081Google Scholar
  4. 4.
    Hill AF, Desbruslais M, Joiner S et al. (1997) The same prion strain causes vCJD and BSE. Nature 389:448–449Google Scholar
  5. 5.
    Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, McCardle L, Chree A, Hope J, Birkett C, Cousens S, Fraser H, Bostock CJ (1997) Transmission to mice indicate that new variant CJD is caused by the BSE agent. Nature 389:498–501PubMedCrossRefGoogle Scholar
  6. 6.
    Duffy P, Wolf J, Collins G, DeVoe AG, Streeten B, Cowen D (1974) Possible person to person transmission of Creutzfeldt-Jakob disease. N Engl J Med 290:693–693Google Scholar
  7. 7.
    Adams DH, Edgar WM (1978) Transmission of agent of Creutzfeldt-Jakob disease. Br Med J 1:987PubMedCentralPubMedCrossRefGoogle Scholar
  8. 8.
    Gibbs CJ Jr., Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC (1994) Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery. J Neurol Neurosurg Psychiatry 57:757–758PubMedCentralPubMedCrossRefGoogle Scholar
  9. 9.
    Heckmann JG, Lang CJ, Petruch F, Druchky A, Erb C, Brown P, Neudorfer B (1997) Transmission of CJD via corneal transplant. J Neurol Neurosurg Psychiatry 63:388–390PubMedCentralPubMedCrossRefGoogle Scholar
  10. 10.
    Will RG, Ironside JW, Zeidler M (1996) A new variant of Creutzfeldt-Jacob disease in the UK. Lancet 347:921–925PubMedCrossRefGoogle Scholar
  11. 11.
    Brown P, Will RG, Bradley R, Asher DM, Detwiler L (2001) Bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease: background, evolution and current concerns. Emerg Infect Dis 7:6–16PubMedCentralPubMedCrossRefGoogle Scholar
  12. 12.
    Lasmézas CI, Fournier JG, Nouvel V, Boe H, Marce D, Lamoury F, Kopp N, Hauw JJ, Ironside J, Bruce M, Dormont D, Deslys JP (2001) Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-Jakob disease: implications for human health. Proc Natl Acad Sci USA 98:4142–4147PubMedCentralPubMedCrossRefGoogle Scholar
  13. 13.
    Hilton DA, Fathers E, Edwards P, Ironside JW, Zajucek J (1998) Prion immunoreactivity in appendix before clinical onset of variant CJD. Lancet 352:703–704Google Scholar
  14. 14.
    Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A, Tollev N, Bell JE, Spencer M, King A, Al-Saarj S, Ironside JW, Lantos PL, Collinge J (1999) Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353:183–189PubMedCrossRefGoogle Scholar
  15. 15.
    Bruce ME, McConnell I, Will RG, Ironside JW (2001) Detection of variant CJD infectivity in extraneural tissues. Lancet 358:208–209PubMedCrossRefGoogle Scholar
  16. 16.
    Ironside JW, Hilton DA, Ghani A, Johnston NJ, Conyers L, McCardle LM, Best D (2000) Retrospective study on prion-protein accumulation in tonsil and appendix tissues. Lancet 355:1693–1694PubMedCrossRefGoogle Scholar
  17. 17.
    Wadsworth JDF, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J (2001) Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jacob disease using a highly sensitive immunoblotting assay. Lancet 358:171–180PubMedCrossRefGoogle Scholar
  18. 18.
    Schreuder BEC, Geertsma RE, van Keulen LJ, van Asten JA, Enthoven P, Oberthur RC, de Koeijer AA, Osterhaus AD (1998) Studies on the efficacy of hyperbaric rendering procedures in inactivating bovine spongiform encephalopathy (BSE) and scrapie agents. Vet Rec 142:474–480PubMedCrossRefGoogle Scholar
  19. 19.
    Rutala WA, Weber DJ (2001) Creutzfeldt-Jakob disease. Recommendations for disinfection and sterilization. Clin Infect Dis 32:1348–1356PubMedCrossRefGoogle Scholar
  20. 20.
    Taylor DM (1999) Inactivation of prions by physical and chemical means. J Hospital Infect 43 [Suppl]:69–76CrossRefGoogle Scholar
  21. 21.
    Taylor DM (2000) Inactivation of transmissible degenerative encephalopathy agents: a review. Vet J 159:10–17PubMedCrossRefGoogle Scholar
  22. 22.
    Block S 2001 Disinfection, sterilization,and preservation, 5th edn. Verlag Lippincolt Williams u.WilkinsGoogle Scholar
  23. 23.
    Risk assessment for transmission of variant CJD via surgical instruments: a modelling approach and numerical scenarios. Economics and Operational Research Division Department of Health, December 2000, London, http://www.doh.gov.uk/cjd/riskassessmentsi.htmGoogle Scholar
  24. 24.
    Laurenson IF, Whyte AS, Fox C, Babb JR (1999) Contaminated surgical instruments and variant Creutzfeldt-Jakob disease. Lancet 354:1823PubMedCrossRefGoogle Scholar
  25. 25.
    Taylor DM, Fraser JR (2000) Letters to the editor/The potential risk of transmitting vCJD through surgery. J Hosp Inf 44:318–319CrossRefGoogle Scholar
  26. 26.
    Axon A, Beilenhoff U, Bramble MG et al. (2001) Variant Creutzfeldt-Jakob disease (vCJD) and gastrointestinal endoscopy. Endoscopy 33:1070–1080Google Scholar
  27. 27.
    Shmakow AN, Gosh S (2001) Prion proteins and the gut: une liaison dangereuse? Gut 48:443–447Google Scholar
  28. 28.
    Kretzschmar HA (2001) BSE und die neue Variante der Creutzfeldt-Jakob-Krankheit. Dtsch Ärztebl 98:A; 40:2576–2583Google Scholar
  29. 29.
    Manuelidis EE, Angelo JN, Gorgacz EJ, Kim JH, Manuelidis L (1977) Experimental CJD transmitted via the eye with infected cornea. N Engl J Med:1334–1337Google Scholar
  30. 30.
    Carp RI (1982) Transmission of scrapie by the oral route: effect of gingival scarification. Lancet:170–171Google Scholar
  31. 31.
    Brown P, Gibbs CJ Jr, Rodger-Johnson P et al. (1994) Human spongiform encephalopathy: The National Institutes of Health Series of 300 cases of experimentally transmitted disease. Ann Neurol 35:513–529Google Scholar
  32. 32.
    Fraser JR (1996) Infectivity in extraneural tissues following intraocular scrapie infection. J Gen Virol 77:2663–2668PubMedCrossRefGoogle Scholar
  33. 33.
    Ingrosso L, Pisani F, Pocchiari M (1999) Transmission of the 263 K scrapie agent by the dental route. J Gen Virol 80:3043–3047PubMedGoogle Scholar
  34. 34.
    Antloga K, Meszaros J, Malchesky PS, McDonnel GE (2000) Prion disease and medical devices. ASAIO J 46:69–72CrossRefGoogle Scholar
  35. 35.
    Schulz-Schaeffer WJ, Beekes W, Kretzschmar H (2001) Die Pathophysiologie von Prionkrankheiten nach peripherer Übertragung. In: Hörnlimann B, Riesner D, Kretzschmar H (Hrsg) Prionen und Prionkrankheiten. De Gruyter, Berlin, S231–235Google Scholar
  36. 36.
    Sautereau D, Palazzo L (2001) Pinces à biopsie à usage unique en endoscopie digestive: sage décision ou caricature du principe de précautation? Gastroenterol Clin Biol 25:653–655PubMedGoogle Scholar
  37. 37.
    Verjat D, Prognon P, Darbold JC (1999) Fluorescence-assay on traces of protein on re-usable medical devices: cleaning efficiency. Int J Pharm 179:267–271PubMedCrossRefGoogle Scholar
  38. 38.
    Brown P, Rohwer RG, Green EM, Gajdusek DC (1982) Effect of chemicals, heat, and histopathologic processing on high-infectivity hamster-adapted scrapie virus. J Infect Dis 145:683–687PubMedCrossRefGoogle Scholar
  39. 39.
    Brown P, Rohwer RG, Gajdusek DC (1986) Newer data on the inactivation of scrapie virus or Creutzfeldt-Jakob disease virus in brain tissue. J Infect Dis 153:1145–1148PubMedCrossRefGoogle Scholar
  40. 40.
    Rohwer RG (1984) Virus-like sensitivity of scrapie agent to heat inactivation. Science 223:600–602PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Personalised recommendations