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Strahlentherapie und Onkologie

, Volume 190, Issue 5, pp 491–493 | Cite as

Radiation recall dermatitis after docetaxel chemotherapy

Treatment by antioxidant ointment
  • Viola Duncker-Rohr
  • Ulrich Freund
  • Felix MommEmail author
Case study

Abstract

Radiation recall dermatitis (RRD) is an acute skin toxicity caused by different anticancer or antibiotic drugs within a former completely healed irradiation field. Predictive factors for RRD are not known and its mechanisms are not completely understood. A case of RRD induced by docetaxel and successfully treated by an antioxidant ointment (Mapisal®) is presented here. Such an ointment might be useful not only in RRD therapy, but also in the treatment of high-grade dermatitis induced by radiotherapy and thus may contribute to the improvement of patients’ quality of life and to the scheduled completion of cancer therapies.

Keywords

Radiation recall reaction Dermatitis Docetaxel Antioxidant ointment Radiotherapy 

Strahlen-Recall-Dermatitis nach Docetaxel-Chemotherapie

Behandlung mit einer antioxidativen Salbe

Zusammenfassung

Die Strahlen-Recall-Dermatitis (RRD) ist eine akute Hauttoxizität, die durch verschiedene Chemotherapeutika oder Antibiotika innerhalb eines früheren, komplett abgeheilten Bestrahlungsfelds hervorgerufen wird. Prädiktive Faktoren für die RRD sind nicht bekannt und ihr Mechanismus ist nicht vollständig geklärt. Es wird ein Fallbericht einer durch Docetaxel induzierten RRD dargestellt, die erfolgreich mit einer antioxidativen Salbe (Mapisal®) behandelt wurde. Solche Salben könnten nicht nur zur Therapie der RRD, sondern auch bei der Behandlung einer akuten Dermatitis während der Strahlentherapie nützlich sein und damit zur Verbesserung der Lebensqualität der Patienten und zur planmäßigen Durchführung der Tumortherapie beitragen.

Schlüsselwörter

Recall-Reaktion Dermatitis Docetaxel Antioxidative Salbe Strahlentherapie 

Notes

Acknowledgments

We thank medac Gesellschaft für klinische Spezialpräparate mbH, Wedel/Germany, for free Mapisal® ointment. We thank our colleagues Dr. Egger and Dr. Scharr, Department of Internal Medicine, Ortenau-Klinikum Lahr, for the perfect cooperation.

Compliance with ethical guidelines

Conflict of interest

V. Duncker-Rohr, U. Freund, and F. Momm state that there are no conflicts of interest.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Radio-OnkologieOrtenau-Klinikum Offenburg-Gengenbach Lehrkrankenhaus der Albert-Ludwigs-Universität Freiburg i. Br.OffenburgGermany

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