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Interaktionen von Leber und Lunge

  • V. Fuhrmann
  • P. Tariparast
Leitthema
  • 46 Downloads

Zusammenfassung

Interaktionen von Leber und Lunge sind im Alltag häufig präsent und von alltäglicher klinischer Relevanz, obwohl sie oft nicht im Fokus der klinischen Aufmerksamkeit stehen. So haben 10 % der Patienten mit akut-auf-chronischem Leberversagen und über 30 % der Patienten in fortgeschrittenen Stadien ein respiratorisches Organversagen. Umgekehrt leiden bis zu 20 % der kritisch kranken Patienten an erworbenen Leberfunktionsstörungen während ihres Intensivstationsaufenthalts. Häufig spielen hierbei auch pulmonale Krankheitsbilder eine zentrale Komponente. Ziel dieses Übersichtsartikels ist es, einen Überblick hinsichtlich der klinisch relevanten erworbenen pulmonalen sowie hepatalen Krankheitsbilder sowie der therapeutischen Optionen bei Leber-Lungen-Interaktionen zu vermitteln.

Schlüsselwörter

Hepatopulmonales Syndrom Atemversagen Pneumonie Leberzirrhose Leberversagen 

Hepatopulmonary interactions

Abstract

Liver–lung interactions are common in daily clinical practice. However, frequently they are not the focus of clinical attention. For example, 10% of patients with acute-on-chronic liver failure and more than 30% of patients with advanced stages of acute-on-chronic liver failure suffer from respiratory failure. Conversely, up to 20% of critically ill patients develop secondary liver failure as a consequence of cardiopulmonary diseases or sepsis during their stay in the intensive care unit. This article provides an overview of clinically relevant liver–lung interactions, consecutively acquired pulmonary and hepatic diseases and the therapeutic implications.

Keywords

Hepatopulmonary syndrome Respiratory failure Pneumonia Liver cirrhosis Liver failure 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

V. Fuhrmann und P. Tariparast geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Klinik für IntensivmedizinUniversitätsklinikum Hamburg-EppendorfHamburgDeutschland
  2. 2.Medizinische Klinik BUniversitätsklinikum MünsterMünsterDeutschland

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