Advertisement

Empfehlungen zur extrakorporalen kardiopulmonalen Reanimation (eCPR)

Konsensuspapier der DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI und GRC
  • G. Michels
  • T. Wengenmayer
  • C. Hagl
  • C. Dohmen
  • B. W. Böttiger
  • J. Bauersachs
  • A. Markewitz
  • A. Bauer
  • J.-T. Gräsner
  • R. Pfister
  • A. Ghanem
  • H.-J. Busch
  • U. Kreimeier
  • A. Beckmann
  • M. Fischer
  • C. Kill
  • U. Janssens
  • S. Kluge
  • F. Born
  • H. M. Hoffmeister
  • M. Preusch
  • U. Boeken
  • R. Riessen
  • H. Thiele
Positionspapier

Zusammenfassung

Die extrakorporale kardiopulmonale Reanimation („extracorporeal cardiopulmonary resuscitation“, eCPR) kann als Rettungsversuch für hoch selektierte Patienten mit refraktärem Herz-Kreislauf-Stillstand und potenziell reversibler Ätiologie erwogen werden. Aktuell fehlen randomisiert-kontrollierte Studien zur eCPR und es existieren keine validen Prädiktoren für Nutzen und Risiko, die bei der Indikationsstellung hilfreich sein könnten. Die bisherigen Selektionskriterien und Abläufe sind klinikspezifisch und ein (nationaler) standardisierter Algorithmus fehlt. Das vorliegende Konsensuspapier bietet basierend auf einer konsentierten Expertenmeinung den Vorschlag für ein standardisiertes Vorgehen bei eCPR.

Schlüsselwörter

Herz-Kreislauf-Stillstand Extrakorporale kardiopulmonale Reanimation Extrakorporale Membranoxygenierung Kardiogener Schock Wiederbelebung 

Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR)

Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC

Abstract

Extracorporeal cardiopulmonary resuscitation (eCPR) may be considered as a rescue attempt for highly selected patients with refractory cardiac arrest and potentially reversible etiology. Currently there are no randomized, controlled studies on eCPR, and valid predictors of benefit and outcome which might guide the indication for eCPR are lacking. Currently selection criteria and procedures differ across hospitals and standardized algorithms are lacking. Based on expert opinion, the present consensus statement provides a proposal for a standardized treatment algorithm for eCPR.

Keywords

Cardiac arrest Extracorporeal cardiopulmonary resuscitation Extracorporeal membrane oxygenation Cardiogenic shock Resuscitation 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

G. Michels ist Mitglied des wissenschaftlichen Beirats der Deutschen Gesellschaft für internistische Intensiv- und Notfallmedizin e. V. (DGIIN), kommissarischer Sprecher der Arbeitsgruppe Kardiopulmonale Reanimation der Deutschen Gesellschaft für Kardiologie e. V. (DGK) sowie Mitglied der Arbeitsgruppe ECMO/eCPR des Deutschen Rats für Wiederbelebung e. V./German Resuscitation Council (GRC) und erhielt Honorare für Vortragstätigkeiten von den Firmen Pfizer, Novartis, Servier, Zoll und Orion Pharma. J. Bauersachs ist Sprecher der DFG-geförderten Klinischen Forschergruppe (KFO) 311 „(Prä-) terminale Herz- und Lungeninsuffizienz: Entlastung und Reparatur“ und erhielt Honorare für Vortragstätigkeiten und Forschungsunterstützung von den Firmen Abiomed und Zoll. B. W. Böttiger ist European Resuscitation Council (ERC) Board Director Science and Research, Vorstandsvorsitzender des Deutschen Rats für Wiederbelebung e. V./German Resuscitation Council (GRC), Mitglied in der „Advanced Cardiac Life Support“ (ALS) Task Force des International Liaison Committee on Resuscitation (ILCOR), Mitglied im Präsidium der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI), Associated Editor des European Journal of Anaesthesiology (EJA), Mitherausgeber der Zeitschrift Resuscitation, Schriftleiter der Zeitschrift Notfall+Rettungsmedizin. Für Vorträge hat er Honorare der folgenden Firmen erhalten: med update GmbH, Forum für Medizinische Fortbildung (FoMF), Baxalta, Bayer Vita, Zoll, BARD. A. Ghanem erhielt Honorare für Vortragstätigkeiten von Getinge. A. Markewitz erhielt ein Vortragshonorar von TÜV Süd, München. J.-T. Gräsner ist 1. Sprecher des Wissenschaftlichen Arbeitskreises Notfallmedizin der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin, Sprecher des Organisationskomitees des Deutschen Reanimationsregisters, Chair des European Registry of Cardiac Arrest, Mitglied im Exekutivkomitee des Deutschen Rats für Wiederbelebung, Mitglied im Präsidium des Berufsverbands Deutscher Anästhesisten. U. Kreimeier ist Leiter der Arbeitsgruppe Advanced Life Support im Deutschen Rat für Wiederbelebung e. V./German Resuscitation Council (GRC). T. Wengenmayer, C. Hagl, C. Dohmen, A. Bauer, R. Pfister, H.-J. Busch, A. Beckmann, M. Fischer, C. Kill, U. Janssens, S. Kluge, F. Born, H. M. Hoffmeister, M. Preusch, U. Boeken, R. Riessen und H. Thiele geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Literatur

  1. 1.
    Atwood C, Eisenberg MS, Herlitz J, Rea TD (2005) Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation 67(1):75–80CrossRefPubMedGoogle Scholar
  2. 2.
    Go AS, Mozaffarian D, Roger VL et al (2014) Executive summary: heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation 129(3):399–410CrossRefPubMedGoogle Scholar
  3. 3.
    Hawkes C, Booth S, Ji C et al (2017) Epidemiology and outcomes from out-of-hospital cardiac arrests in England. Resuscitation 110:133–140CrossRefPubMedGoogle Scholar
  4. 4.
    Spangenberg T, Schewel J, Dreher A et al (2018) Health related quality of life after extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest. Resuscitation 127:73–78CrossRefPubMedGoogle Scholar
  5. 5.
    Kuisma M, Alaspää A (1997) Out-of-hospital cardiac arrests of non-cardiac origin. Epidemiology and outcome. Eur Heart J 18(7):1122–1128CrossRefPubMedGoogle Scholar
  6. 6.
    Hess EP, Campbell RL, White RD (2007) Epidemiology, trends, and outcome of out-of-hospital cardiac arrest of non-cardiac origin. Resuscitation 72(2):200–206CrossRefPubMedGoogle Scholar
  7. 7.
    Sandroni C, Nolan J, Cavallaro F, Antonelli M (2007) In-hospital cardiac arrest: Incidence, prognosis and possible measures to improve survival. Intensive Care Med 33:237–245CrossRefPubMedGoogle Scholar
  8. 8.
    Link MS, Berkow LC, Kudenchuk PJ et al (2015) Part 7: advanced cardiovascular life support – 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 132(Suppl 2):S444–S464CrossRefPubMedGoogle Scholar
  9. 9.
    Karam N, Marijon E, Dumas F et al (2017) Characteristics and outcomes of out-of-hospital sudden cardiac arrest according to the time of occurrence. Resuscitation 116:16–21CrossRefPubMedGoogle Scholar
  10. 10.
    Soar J, Nolan JP, Böttiger BW et al (2015) European Resuscitation Council guidelines for resuscitation 2015 Section 3. Adult advanced life support. Resuscitation 95:100–147CrossRefPubMedGoogle Scholar
  11. 11.
    Kim SJ, Kim HJ, Lee HY et al (2016) Comparing extracorporeal cardiopulmonary resuscitation with conventional cardiopulmonary resuscitation: a meta-analysis. Resuscitation 103:106–116CrossRefPubMedGoogle Scholar
  12. 12.
    Vdovin N, Günther SPW, de Waha S et al (2017) Early risk stratification in patients with cardiogenic shock complicating acute myocardial infarction treated with extracorporeal life support and primary percutaneous coronary intervention. JACC Cardiovasc Interv 10(23):2469–2471CrossRefPubMedGoogle Scholar
  13. 13.
    Chen YS, Lin JW, Yu HY et al (2008) Cardiopulmonary resuscitation with assisted extracorporeal life support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet 372:554–561CrossRefPubMedGoogle Scholar
  14. 14.
    Wang CH, Chou NK, Becker LB et al (2014) Improved outcome of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest – a comparison with that for extracorporeal rescue for in-hospital cardiac arrest. Resuscitation 85(9):1219–1224CrossRefPubMedGoogle Scholar
  15. 15.
    Fagnoul D, Combes A, De Backer D (2014) Extracorporeal cardiopulmonary resuscitation. Curr Opin Crit Care 20(3):259–265CrossRefPubMedGoogle Scholar
  16. 16.
    Blumenstein J, Leick J, Liebetrau C et al (2016) Extracorporeal life support in cardiovascular patients with observed refractory in-hospital cardiac arrest is associated with favourable short and long-term outcomes: a propensity-matched analysis. Eur Heart J Acute Cardiovasc Care 5(7):13–22CrossRefPubMedGoogle Scholar
  17. 17.
    Spangenberg T, Meincke F, Brooks S et al (2016) „Shock and Go?“ extracorporeal cardio-pulmonary resuscitation in the golden-hour of ROSC. Catheter Cardiovasc Interv 88(5):691–696CrossRefPubMedGoogle Scholar
  18. 18.
    Combes A, Brodie D, Chen YS et al (2017) The ICM research agenda on extracorporeal life support. Intensive Care Med 43(9):1306–1318CrossRefPubMedGoogle Scholar
  19. 19.
    Debaty G, Babaz V, Durand M et al (2017) Prognostic factors for extracorporeal cardiopulmonary resuscitation recipients following out-of-hospital refractory cardiac arrest. A systematic review and meta-analysis. Resuscitation 112:1–10CrossRefPubMedGoogle Scholar
  20. 20.
    Conrad SA, Rycus PT (2017) Extracorporeal membrane oxygenation for refractory cardiac arrest. Ann Card Anaesth 20(Supplement):S4–S10CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    Richardson AS, Schmidt M, Bailey M et al (2017) ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years. Resuscitation 112:34–40CrossRefPubMedGoogle Scholar
  22. 22.
    Haas NL, Coute RA, Hsu CH et al (2017) Descriptive analysis of extracorporeal cardiopulmonary resuscitation following out-of-hospital cardiac arrest-an ELSO registry study. Resuscitation 119:56–62CrossRefPubMedPubMedCentralGoogle Scholar
  23. 23.
    Ouweneel DM, Schotborgh JV, Limpens J et al (2016) Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis. Intensive Care Med 42:1922–1934CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Trummer G, Bein B, Buerke M et al (2011) Standardized terminology of mechanical heart, lung and circulatory assist devices: a recommendation of the section „heart and circulation“ of the German Interdisciplinary Association of Critical Care Medicine. Appl Cardiopulm Pathophysiol 15:181–182Google Scholar
  25. 25.
  26. 26.
    Günther S, Born F, Buchholz S et al (2018) Patienten unter Reanimation: Kandidaten für „Extracorporeal Life Support“? Z Herz Thorax Gefäßchir 32:133–140CrossRefGoogle Scholar
  27. 27.
    Wengenmayer T, Rombach S, Ramshorn F et al (2017) Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR). Crit Care 21(1):157CrossRefPubMedPubMedCentralGoogle Scholar
  28. 28.
    Kuroki N, Abe D, Iwama T et al (2017) Association between delay to coronary reperfusion and outcome in patients with acute coronary syndrome undergoing extracorporeal cardiopulmonary resuscitation. Resuscitation 114:1–6CrossRefPubMedGoogle Scholar
  29. 29.
    Abrams D, Garan AR, Abdelbary A et al (2018) Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive Care Med.  https://doi.org/10.1007/s00134-018-5064-5 CrossRefPubMedGoogle Scholar
  30. 30.
    Yannopoulos D, Bartos JA, Raveendran G et al (2017) Coronary artery disease in patients with out-of-hospital refractory ventricular fibrillation cardiac arrest. J Am Coll Cardiol 70(9):1109–1117CrossRefPubMedGoogle Scholar
  31. 31.
    Hayashida K, Suzuki M, Yonemoto N et al (2017) Early lactate clearance is associated with improved outcomes in patients with postcardiac arrest syndrome: a prospective, multicenter observational study (SOS-KANTO 2012 study). Crit Care Med 45(6):e559–e566CrossRefPubMedGoogle Scholar
  32. 32.
    Slottosch I, Liakopoulos O, Kuhn E et al (2017) Lactate and lactate clearance as valuable tool to evaluate ECMO therapy in cardiogenic shock. J Crit Care 42:35–41CrossRefPubMedGoogle Scholar
  33. 33.
    Momiyama Y, Yamada W, Miyata K et al (2017) Prognostic values of blood pH and lactate levels in patients resuscitated from out-of-hospital cardiac arrest. Acute Med Surg 4(1):25–30CrossRefPubMedGoogle Scholar
  34. 34.
    Zeserson E, Goodgame B, Hess JD et al (2018) Correlation of venous blood gas and pulse oximetry with arterial blood gas in the undifferentiated critically ill patient. J Intensive Care Med 33(3):176–181CrossRefPubMedGoogle Scholar
  35. 35.
    Siegenthaler W (2005) Differentialdiagnose, 19. Aufl. Thieme, StuttgartGoogle Scholar
  36. 36.
    Geisler AC, Söffker G, Breunig F et al (2014) Der besondere Fall-Optimale Rettungskette. Hamb Arztebl 68(10):44–46Google Scholar
  37. 37.
    Hohmann C, Pfister R, Michels G (2018) Are the initial pH and the lactate values after cardiopulmonary resuscitation always crucial? Med Klin Intensivmed Notfmed.  https://doi.org/10.1007/s00063-018-0432-z PubMedCrossRefGoogle Scholar
  38. 38.
    Shin J, Lim YS, Kim K et al (2017) Initial blood pH during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a multicenter observational registry-based study. Crit Care 21(1):322CrossRefPubMedPubMedCentralGoogle Scholar
  39. 39.
    Gil E, Na SJ, Ryu JA et al (2017) Association of body mass index with clinical outcomes for in-hospital cardiac arrest adult patients following extracorporeal cardiopulmonary resuscitation. PLoS ONE 12(4):e176143CrossRefPubMedPubMedCentralGoogle Scholar
  40. 40.
    Kang SB, Kim KS, Suh GJ et al (2017) Long-term survival of out-of-hospital cardiac arrest patients with malignancy. Am J Emerg Med 35(10):1457–1461CrossRefPubMedGoogle Scholar
  41. 41.
    Sulzgruber P, Sterz F, Poppe M et al (2017) Age-specific prognostication after out-of-hospital cardiac arrest - the ethical dilemma between „life-sustaining treatment“ and „the right to die“ in the elderly. Eur Heart J Acute Cardiovasc Care 6(2):112–120CrossRefPubMedGoogle Scholar
  42. 42.
    Pabst D, El-Banayosy A, Soleimani B, Brehm CE (2018) Predictors of survival for nonhighly selected patients undergoing resuscitation with extracorporeal membrane oxygenation after cardiac arrest. ASAIO J 64(3):368–374CrossRefPubMedGoogle Scholar
  43. 43.
    Lorusso R, Gelsomino S, Parise O et al (2017) Venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock in elderly patients: trends in application and outcome from the Extracorporeal Life Support Organization (ELSO) Registry. Ann Thorac Surg 104(1):62–69CrossRefPubMedGoogle Scholar
  44. 44.
    Riggs KR, Becker LB, Sugarman J (2015) Ethics in the use of extracorporeal cardiopulmonary resuscitation in adults. Resuscitation 91:73–75CrossRefPubMedPubMedCentralGoogle Scholar
  45. 45.
    Mancini ME, Diekema DS, Hoadley TA et al (2015) Part 3: ethical issues: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 132(18 Suppl 2):S383–S396CrossRefPubMedGoogle Scholar
  46. 46.
    Meltzer EC, Ivascu NS, Stark M et al (2016) A survey of physicians’ attitudes toward decision-making authority for initiating and withdrawing VA-ECMO: results and ethical implications for shared decision making. J Clin Ethics 27(4):281–289PubMedPubMedCentralGoogle Scholar
  47. 47.
    Makdisi T, Makdisi G (2017) Extra-corporeal membrane oxygenation support: ethical dilemmas. Ann Transl Med 5(5):112CrossRefPubMedPubMedCentralGoogle Scholar
  48. 48.
    Niecke A, Schneider G, Hartog CS, Michels G (2017) Traumatized relatives of intensive care patients. Med Klin Intensivmed Notfmed 112(7):612–617CrossRefPubMedGoogle Scholar
  49. 49.
    Michels G, Thiele H, Kluge S, Pfister R (2017) Are there any prognostic predictors for extracorporeal cardiopulmonary resuscitation (ECPR) in case of out-of-hospital cardiac arrest? Med Klin Intensivmed Notfmed 112(7):634–636CrossRefPubMedGoogle Scholar
  50. 50.
    Stiell IG, Nichol G, Leroux BG et al (2011) Early versus later rhythm analysis in patients with out-of-hospital cardiac arrest. N Engl J Med 365(9):787–797CrossRefPubMedPubMedCentralGoogle Scholar
  51. 51.
    Goslar T, Knafelj R, Radsel P et al (2016) Emergency percutaneous implantation of veno-arterial extracorporeal membrane oxygenation in the catheterisation laboratory. EuroIntervention 12(12):1465–1472CrossRefPubMedGoogle Scholar
  52. 52.
    Kashiura M, Sugiyama K, Tanabe T, Akashi A, Hamabe Y (2017) Effect of ultrasonography and fluoroscopic guidance on the incidence of complications of cannulation in extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest: a retrospective observational study. BMC Anesthesiol 17(1):4CrossRefPubMedPubMedCentralGoogle Scholar
  53. 53.
    Voicu S, Henry P, Malissin I et al (2018) Improving cannulation time for extracorporeal life support in refractory cardiac arrest of presumed cardiac cause – comparison of two percutaneous cannulation techniques in the catheterization laboratory in a center without on-site cardiovascular surgery. Resuscitation 122:69–75CrossRefPubMedGoogle Scholar
  54. 54.
    Reynolds JC, Callaway CW, El Khoudary SR et al (2009) Coronary angiography predicts improved outcome following cardiac arrest: propensity-adjusted analysis. J Intensive Care Med 24(3):179–186CrossRefPubMedPubMedCentralGoogle Scholar
  55. 55.
    Dumas F, Cariou A, Manzo-Silberman S et al (2010) Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT (Parisian Region Out of hospital Cardiac ArresT) registry. Circ Cardiovasc Interv 3(3):200–207CrossRefPubMedGoogle Scholar
  56. 56.
    Kragholm K, Malta Hansen C, Dupre ME et al (2017) Direct transport to a percutaneous cardiac intervention center and outcomes in patients with out-of-hospital cardiac arrest. Circ Cardiovasc Qual Outcomes 10(6):e3414.  https://doi.org/10.1161/CIRCOUTCOMES.116.003414 CrossRefPubMedGoogle Scholar
  57. 57.
    Scholz KH, Andresen D, Böttiger BW et al (2017) Quality indicators and structural requirements for cardiac arrest centers-German Resuscitation Council (GRC). Kardiologe 11:205–208CrossRefGoogle Scholar
  58. 58.
    Jarosz A, Darocha T, Kosiński S et al (2017) Profound accidental hypothermia: systematic approach to active recognition and treatment. ASAIO J 63(3):e26–e30CrossRefPubMedPubMedCentralGoogle Scholar
  59. 59.
    Beckmann A, Benk C, Beyersdorf F et al (2011) Position article for the use of extracorporeal life support in adult patients. Eur J Cardiothorac Surg 40(3):676–680PubMedGoogle Scholar
  60. 60.
    Combes A, Brodie D, Bartlett R et al (2014) Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. Am J Respir Crit Care Med 190(5):488–496CrossRefPubMedGoogle Scholar
  61. 61.
    Dirnberger D, Fiser R, Harvey C et al (2015) Extracorporeal Life Support Organization (ELSO), guidelines for ECMO transport. https://www.elso.org/resources/guidelines.aspx Google Scholar
  62. 62.
    Broman LM, Frenckner B (2016) Transportation of critically ill patients on extracorporeal membrane oxygenation. Front Pediatr 4:63CrossRefPubMedPubMedCentralGoogle Scholar
  63. 63.
    Michels G, Zinke H, Möckel M et al (2017) Recommendations for education in ultrasound in medical intensive care and emergency medicine: position paper of DGIIN, DEGUM and DGK. Med Klin Intensivmed Notfmed 112(4):314–319CrossRefPubMedGoogle Scholar
  64. 64.
    Zhang Z (2017) Echocardiography for patients undergoing extracorporeal cardiopulmonary resuscitation: a primer for intensive care physicians. J Intensive Care 5:15CrossRefPubMedPubMedCentralGoogle Scholar
  65. 65.
    Price S, Platz E, Cullen L et al (2017) Expert consensus document: echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nat Rev Cardiol 14(7):427–440CrossRefPubMedPubMedCentralGoogle Scholar
  66. 66.
    Nolan JP, Hazinski MF, Aickin R et al (2015) Part 1: executive summary: 2015 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Resuscitation 95:e1–e31CrossRefPubMedGoogle Scholar
  67. 67.
    Olasveengen TM, de Caen AR, Mancini ME et al (2017) 2017 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations summary. Circulation 136(23):e424–e440CrossRefPubMedGoogle Scholar
  68. 68.
    Perkins GD, Olasveengen TM, Maconochie I et al (2018) European Resuscitation Council guidelines for resuscitation: 2017 update. Resuscitation 123:43–50CrossRefPubMedGoogle Scholar
  69. 69.
    Swol J, Belohlávek J, Haft JW et al (2016) Conditions and procedures for in-hospital extracorporeal life support (ECLS) in cardiopulmonary resuscitation (CPR) of adult patients. Perfusion 31(3):182–188CrossRefPubMedGoogle Scholar
  70. 70.
    Leick J, Liebetrau C, Szardien S et al (2013) Door-to-implantation time of extracorporeal life support systems predicts mortality in patients with out-of-hospital cardiac arrest. Clin Res Cardiol 102(9):661–669CrossRefPubMedGoogle Scholar
  71. 71.
    Nanjayya VB, Murphy D (2015) Ultrasound guidance for extra-corporeal membrane oxygenation general guidelines (https://www.elso.org/Portals/0/Files/elso_Ultrasoundguideance_ecmogeneral_guidelines_May2015.pdf)Google Scholar
  72. 72.
    Ahn HJ, Lee JW, Joo KH et al (2018) Point-of-care ultrasound-guided percutaneous cannulation of extracorporeal membrane oxygenation: make it simple. J Emerg Med 54(4):507–513CrossRefPubMedGoogle Scholar
  73. 73.
    Beck L, Burg MC, Heindel W, Schülke C (2017) Extracorporeal membrane oxygenation in adults – variants, complications during therapy, and the role of radiological imaging. Rofo 189(2):119–127PubMedGoogle Scholar
  74. 74.
    Pang PY, Wee GH, Hoo AE et al (2016) Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study. J Cardiothorac Surg 11:43CrossRefPubMedPubMedCentralGoogle Scholar
  75. 75.
    Spartera M, Jabbour RJ, Chiarito M, De Bonis M, Pappalardo F (2017) Stepwise use of circulatory support devices in a patient refractory to cardiopulmonary resuscitation. Cardiovasc Revasc Med 18(6):447–449CrossRefPubMedGoogle Scholar
  76. 76.
    Tepper S, Masood MF, Baltazar Garcia M et al (2017) Left ventricular unloading by Impella device versus surgical vent during extracorporeal life support. Ann Thorac Surg 104(3):861–867CrossRefPubMedGoogle Scholar
  77. 77.
    Ibanez B, James S, Agewall S et al (2018) 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 39(2):119–177 (The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC))CrossRefPubMedGoogle Scholar
  78. 78.
    Johnson B, Runyon M, Weekes A, Pearson D (2017) Team-focused cardiopulmonary resuscitation: prehospital principles adapted for emergency department cardiac arrest resuscitation. J Emerg Med.  https://doi.org/10.1016/j.jemermed.2017.08.065 CrossRefPubMedGoogle Scholar
  79. 79.
    Barbaro RP, Odetola FO, Kidwell KM et al (2015) Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry. Am J Respir Crit Care Med 191(8):894–901CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  • G. Michels
    • 1
  • T. Wengenmayer
    • 2
  • C. Hagl
    • 3
  • C. Dohmen
    • 4
  • B. W. Böttiger
    • 5
  • J. Bauersachs
    • 6
  • A. Markewitz
    • 7
  • A. Bauer
    • 8
  • J.-T. Gräsner
    • 9
  • R. Pfister
    • 1
  • A. Ghanem
    • 10
  • H.-J. Busch
    • 11
  • U. Kreimeier
    • 12
  • A. Beckmann
    • 13
  • M. Fischer
    • 14
  • C. Kill
    • 15
  • U. Janssens
    • 16
  • S. Kluge
    • 17
  • F. Born
    • 3
  • H. M. Hoffmeister
    • 18
  • M. Preusch
    • 19
  • U. Boeken
    • 20
  • R. Riessen
    • 21
  • H. Thiele
    • 22
  1. 1.Klinik III für Innere Medizin, HerzzentrumUniversität zu KölnKölnDeutschland
  2. 2.Klinik für Kardiologie und Angiologie I, Universitäts-Herzzentrum Freiburg – Bad KrozingenMedizinische Fakultät der Albert-Ludwigs-Universität FreiburgFreiburgDeutschland
  3. 3.Herzchirurgische Klinik und Poliklinik, Klinikum der Universität MünchenLudwig-Maximilians-UniversitätMünchenDeutschland
  4. 4.LVR-Klinik BonnBonnDeutschland
  5. 5.Klinik für Anästhesiologie und Operative IntensivmedizinUniversität zu KölnKölnDeutschland
  6. 6.Klinik für Kardiologie und AngiologieMedizinische Hochschule HannoverHannoverDeutschland
  7. 7.BendorfDeutschland
  8. 8.MediClin Herzzentrum CoswigCoswigDeutschland
  9. 9.Institut für Rettungs- und NotfallmedizinUniversitätsklinikum Schleswig-HolsteinKielDeutschland
  10. 10.Abteilung Kardiologie, II. Medizinische KlinikAsklepios Klinik St. GeorgHamburgDeutschland
  11. 11.Universitäts-NotfallzentrumUniversitätsklinikum Freiburg, Medizinische Fakultät der Albert-Ludwigs-Universität FreiburgFreiburgDeutschland
  12. 12.Klinik für Anästhesiologie, Klinikum der Universität MünchenLudwig-Maximilians-UniversitätMünchenDeutschland
  13. 13.Herzzentrum Duisburg, Klinik für Herz- und GefäßchirurgieEvangelisches Krankenhaus NiederrheinDuisburgDeutschland
  14. 14.Klinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und SchmerztherapieALB FILS KLINIKEN GmbH, Klinik am EichertGöppingenDeutschland
  15. 15.Zentrum für NotfallmedizinUniversitätsmedizin EssenEssenDeutschland
  16. 16.Klinik für Innere Medizin und IntensivmedizinSt.-Antonius-HospitalEschweilerDeutschland
  17. 17.Klinik für IntensivmedizinUniversitätsklinikum Hamburg-EppendorfHamburgDeutschland
  18. 18.Klinik für Kardiologie und Allgemeine Innere MedizinStädtisches Klinikum Solingen gGmbHSolingenDeutschland
  19. 19.Zentrum für Innere Medizin, Klinik für Kardiologie, Angiologie und PneumologieUniversitätsklinikum HeidelbergHeidelbergDeutschland
  20. 20.Klinik für Kardiovaskuläre Chirurgie, Universitätsklinikum DüsseldorfHeinrich-Heine-Universität DüsseldorfDüsseldorfDeutschland
  21. 21.Department für Innere Medizin, Internistische IntensivstationUniversitätsklinikum TübingenTübingenDeutschland
  22. 22.Klinik für Innere Medizin/KardiologieHerzzentrum Leipzig – UniversitätsklinikLeipzigDeutschland

Personalised recommendations