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Isolated Intracranial Myeloid Sarcoma at Age 6 Months with Metastases

Case Report and Review of the Literature
  • Jianbin Zhu
  • Sujan Thapa
  • Xianlong Wang
  • Chunxiu Jiang
  • Yaoming Qu
  • Zhibo WenEmail author
Correspondence

Introduction

Myeloid sarcoma (MS) is a neoplasm formed by the infiltration of protogranulocytes or immature myeloid cells into organs and tissues other than bone marrow [1]. It can be associated with acute myeloid leukemia (AML) or chronic myeloid leukemia (CML) and other myeloproliferative disorders at the same time or before or after [2]. Isolated MS is defined as the disease without evidence of AML in bone marrow biopsy and failure to develop into AML within 30 days after the diagnosis of MS, which has an incidence of approximately 2 out of 1 million adults and 0.7 out of 1 million children; however, in infants it is even rarer [3, 4]. An MS can invade any anatomical site [1], the occurrence of MS in the central nervous system (CNS) is rare [5] and isolated primary intracranial MS should be carefully considered. This article presents a unique case of isolated intracranial MS at in a 6‑month-old patient with extensive brain metastases to highlight the unusual clinical and imaging...

Notes

Conflict of interest

J. Zhu, S. Thapa, X. Wang, C. Jiang, Y. Qu and Z. Wen declare that they have no competing interests.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Jianbin Zhu
    • 1
  • Sujan Thapa
    • 1
  • Xianlong Wang
    • 1
  • Chunxiu Jiang
    • 1
  • Yaoming Qu
    • 1
  • Zhibo Wen
    • 1
    Email author
  1. 1.Department of Radiology, Zhujiang HospitalSouthern Medical UniversityGuangzhouChina

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