Risk Factors of Procedural Complications Related to Woven EndoBridge (WEB) Embolization of Intracranial Aneurysms

  • Lukas GoertzEmail author
  • Thomas Liebig
  • Eberhard Siebert
  • Moriz Herzberg
  • Hannah Neuschmelting
  • Jan Borggrefe
  • Özgür A. Onur
  • Franziska Dorn
  • Christoph Kabbasch
Original Article



The Woven EndoBridge (WEB) device has been proven to be a safe and efficient endovascular treatment option for wide-necked bifurcation aneurysms. The study aimed to evaluate the incidence and risk factors of procedural complications related to WEB embolization of ruptured and unruptured intracranial aneurysms.


This was a multicenter, observational study of consecutive patients with ruptured and unruptured aneurysms who were treated with the WEB at three German tertiary care centers between May 2011 and February 2018. Patient characteristics, anatomical details and procedural aspects were retrospectively collected and the impact on procedure-related complications was evaluated.


Among 120 patients (mean age 58.5 ± 11.9 years) with 120 aneurysms (mean size: 8.5 ± 4.5 mm), WEB implantation was successful in 112 patients (93.3%). The rates for overall and symptomatic complications were 11.7% and 5.0%, respectively. At 6‑month follow-up device-related morbidity was 1.2% among unruptured aneurysms and 2.6% among ruptured aneurysms. In the univariate analysis, a lower aspect ratio (p = 0.04) and an increased width-to-height ratio (p = 0.03) were significant risk factors for procedural complications.


The results of this study confirmed the WEB to be a safe treatment option, which is associated with low complication rates and minimal morbidity. Complications tended to occur more often in aneurysms with an unfavorable ratio between aneurysm height and aneurysm/neck width.


Aneurysm Complication Subarachnoid hemorrhage WEB Woven Endobridge 



This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

Compliance with ethical guidelines

Conflict of interest

L. Goertz, E. Siebert, M. Herzberg, H. Neuschmelting, J. Borggrefe, Ö.A. Onur declare that they have no competing interests. T. Liebig serves as proctor for MicroVention Inc./Sequent Medical (Aliso Viejo, CA, USA). F. Dorn and C. Kabbasch serve as consultants for Acandis GmbH (Pforzheim, Germany).

Ethical standards

All procedures reported in this article were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. According to institutional guidelines, no ethics committee approval was required for this retrospective observational study. The manuscript does not contain any details that might disclose the identity of the patients.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of NeuroradiologyUniversity Hospital of CologneCologneGermany
  2. 2.Center for NeurosurgeryUniversity Hospital of CologneCologneGermany
  3. 3.Department of NeuroradiologyUniversity Hospital Munich (LMU)MunichGermany
  4. 4.Department of NeuroradiologyUniversity Hospital of Berlin (Charité)BerlinGermany
  5. 5.Department of NeurologyUniversity Hospital of CologneCologneGermany

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