Clinical Neuroradiology

, Volume 28, Issue 2, pp 201–207 | Cite as

First Experiences with the New Enterprise2® Stent

  • C. Herweh
  • S. Nagel
  • J. Pfaff
  • C. Ulfert
  • M. Wolf
  • M. Bendszus
  • M. Möhlenbruch
Original Article



Stent-assisted coiling of wide-necked intracranial aneurysms has become an established treatment and has significantly benefited from the introduction of compliant, self-expanding devices, such as the Enterprise VRD (EP-VRD). We report our experiences with the successor model, the Enterprise2 (EP2) stent in stent-assisted coiling as well as in the treatment of atherosclerotic stenosis.

Materials and Methods

In 11 consecutive patients 12 EP2 were used to treat 9 intracranial aneurysms and 2 stenoses.


All stents could easily be delivered including partial or complete recapturing when necessary. In two cases with sharp angled curves in the carotid siphon there was kinking and flattening of the stent resulting in incomplete wall apposition of the stent. Moreover, when vascular anatomy showed curves with angles >50° it was regularly observed that the proximal stent markers were asymmetrically arranged along the vessel circumference without influence on the stent apposition. Both findings could be reproduced in a silicone flow model.


The EP2 performed well in our small patient cohort; however, above a critical acute angle there may be incomplete wall apposition of the stent.


Aneurysm Endovascular Stent Enterprise Coiling 


Compliance with Ethical Guidelines

Conflict of Interest

C. Herweh, S. Nagel, J. Pfaff, C. Ulfert, M. Wolf, M. Bendszus and M. Möhlenbruch declare that they have no competing interests.

Ethical standards

This study was conducted in accordance with the Declaration of Helsinki in its current version and the current version of ICH-GCP principles and was approved by our local ethics committee (ethics committee of the University of Heidelberg; ID: S‑247/2009). All patients gave written and informed consent.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • C. Herweh
    • 1
  • S. Nagel
    • 2
  • J. Pfaff
    • 1
  • C. Ulfert
    • 1
  • M. Wolf
    • 1
  • M. Bendszus
    • 1
  • M. Möhlenbruch
    • 1
  1. 1.Department of NeuroradiologyUniversity of Heidelberg Medical CenterHeidelbergGermany
  2. 2.Department of NeurologyUniversity of Heidelberg Medical CenterHeidelbergGermany

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