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, Volume 49, Issue 1, pp 28–36 | Cite as

Von harmlosen Aphthen bis zu fortgeschrittenen Leukoplakien

Krankheiten der oralen Mukosa

  • Thomas DirschkaEmail author
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Zusammenfassung

Erkrankungen der Mundschleimhaut sind häufig gutartig und selbstlimitierend. Dieser Umstand kann jedoch dazu führen, dass infektiöse Ulzerationen oder gar Karzinome als harmlos fehlinterpretiert werden. Eine genaue Kenntnis der Differenzialdiagnosen und eine sorgfältige Untersuchung des Patienten sind daher unerlässlich.

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Literatur

  1. 1.
    Khudhur et al. Oral lichenoid tissue reactions: diagnosis and classification. Exp Rev Mol Diag 2014; 14: 169–84CrossRefGoogle Scholar
  2. 2.
    Lavanya N et al. Oral lichen planus: An update on pathogenesis and treatment. J Oral Maxillofac Pathol 2011; 15: 127–32CrossRefGoogle Scholar
  3. 3.
    Gorouhi F et al. Cutaneous and mucosal lichen planus: A comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. ScientificWorldJournal 2014; 742826Google Scholar
  4. 4.
    Eisen D. The clinical manifestations and treatment of oral lichen planus. Dermatol Clin 2003; 21: 79–89CrossRefGoogle Scholar
  5. 5.
    Rapp U et al. Investigation of contact allergy to dental metals in 206 patients. Contact Dermatitis 2009; 60: 339–43CrossRefGoogle Scholar
  6. 6.
    Yiannias JA et al. Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. J Am Acad Dermatol 2000; 42: 177–82CrossRefGoogle Scholar
  7. 7.
    Feller L et al. Review: allergic contact stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol 2017; 123: 559–65CrossRefGoogle Scholar
  8. 8.
    Suresh SS et al. Medical management of oral lichen planus: A systematic review. J Clin Diagn Res 2016; 10: 10–5Google Scholar
  9. 9.
    Sonthalia S et al. Comparative efficacy of tacrolimus 0,1 % ointment and clobetasol 0,05 % ointment in oral lichen planus: a randomized double-blind trial. Int J Dermatol 2012; 51: 1371–8CrossRefGoogle Scholar
  10. 10.
    Yoke PC et al. A randomized controlled trial to compare steroid with cyclosporine for the topical treatment of lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 47–55CrossRefGoogle Scholar
  11. 11.
    Olson KA et al. Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease. Pharmacotherapy 2014; 34: 60–4CrossRefGoogle Scholar
  12. 12.
    Goodson ML et al. Efficacy of oral brush biopsy in potentially malignant disorder management. J Oral Pathol Med 2017; 46: 896–901PubMedGoogle Scholar
  13. 13.
    Cai W et al. Current approaches to the diagnosis and treatment of white sponge nevus. Expert Rev Mol Med 2015; 17: e9CrossRefGoogle Scholar
  14. 14.
    Zeidan MJ et al. Behçet’s disease physiopathology: A contemporary review. Auto Immun Highlights. 2016; 7: 4CrossRefGoogle Scholar
  15. 15.
    International Team for the Revision of the International Criteria for Behçet’s Disease (ITRICBD). The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014; 28: 338–47Google Scholar
  16. 16.
    Alpsoy E. Behçet’s disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions. J Dermatol 2016; 43: 620–32CrossRefGoogle Scholar
  17. 17.
    Hatemi G et al. Apremilast for Behçet’s syndrome — a phase 2, placebo-controlled study. N Engl J Med 2015; 372: 1510–8CrossRefGoogle Scholar
  18. 18.
    Liang MW et al. Oral Aphthosis. Management gaps and recent advances. Ann Acad Med Singapore 2012; 41: 463–70PubMedGoogle Scholar
  19. 19.
    S2k-Leitlinie (Langversion): Diagnostik und Therapieoptionen von Aphthen und aphthoiden Läsionen der Mund- und Rachenschleimhaut. AWMF-Registernummer: 007-101, Stand: November 2016Google Scholar
  20. 20.
    Altenburg A et al. Behandlung chronisch-rezidivierender oraler Aphthen. Dtsch Arztebl Int 2014; 111: 665–73PubMedPubMedCentralGoogle Scholar
  21. 21.
    Horváth ON et al. Entzündliche orale Schleimhautkrankheiten. Hautarzt 2016; 67: 786–92CrossRefGoogle Scholar
  22. 22.
    Benoit S et al. Differenzialdiagnose erosiver und ulzeröser Mundschleimhautkrankheiten im Kindesalter. Hautarzt 2015; 66: 258–66CrossRefGoogle Scholar
  23. 23.
    Akintoye SO et al. Recurrent aphthous stomatitis. Dent Clin North Am. 2014; 58: 281–97CrossRefGoogle Scholar
  24. 24.
    Dhanrajani P et al. Oral eosinophilic or traumatic ulcer: A case report and brief review. Natl J Maxillofac Surg 2015; 6: 237–40CrossRefGoogle Scholar
  25. 25.
    Lengfeld J et al. Biphosphonate-mediated oral ulcers: A rare diagnosis of erosive oral lesions. Dermatology 2016; 232: 117–21CrossRefGoogle Scholar
  26. 26.
    Lambertini M et al. Oral melanoma and other pigmentations: when to biopsy? J Eur Acad Dermato Venereol 2017; http://doi.org/10.111/jdv.14574Google Scholar
  27. 27.
    Al-Ansari S et al. Oral mucositis induced by anticancer therapies. Curr Oral Health Rep 2014; 2: 202–11CrossRefGoogle Scholar
  28. 28.
    Buglione M et al. Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement. Crit Rev Oncol Hematol 2016; 102: 47–54CrossRefGoogle Scholar
  29. 29.
    Edens MH et al. Intraoral pain disorders. Oral Maxillofac Surg Clin North Am 2016; 28: 275–88CrossRefGoogle Scholar
  30. 30.
    Chaveli-López B et al. Treatment of oral mucositis due to chemotherapy. J Clin Exp Dent 2016; 8: e201–9PubMedPubMedCentralGoogle Scholar
  31. 31.
    De Sanctis V et al. Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus statements. Crit Rev Oncol Hematol 2016; 100: 147–66CrossRefGoogle Scholar
  32. 32.
    Delli K et al. Xerostomia. Monogr Oral Sci 2014; 24: 109–25CrossRefGoogle Scholar
  33. 33.
    Manzi Nde M et al. Prophylaxis for mucositis induced by ambulatory chemotherapy: Systematic review. J Adv Nurs 2016; 72: 735–46CrossRefGoogle Scholar
  34. 34.
    Tanasiewicz M et al. Xerostomia of various etiologies: A review of the literature. Adv Clin Exp Med 2016; 25: 199–206CrossRefGoogle Scholar
  35. 35.
    Cuba LF et al. Cannabidiol: an alternative therapeutic agent for oral mucositis? J Clin Pharm Ther 2017; 42: 245–50CrossRefGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2019

Authors and Affiliations

  1. 1.Centroderm Klinik WuppertalWuppertalDeutschland

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