Herz

, Volume 37, Issue 3, pp 347–354 | Cite as

Aneurysmatic disease in patients with Takayasu disease: a case review

Case study
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Abstract

Takayasu disease is a non-specific inflammatory disease of the arterial system. Although various etiopathogenetic hypotheses have been formulated, its etiology remains unknown. The aorta and its main branches are predominantly involved in the disease, which is a form of panarteritis, starting with inflammation of the adventitia followed by involvement of the media and intima. It has been more frequently described in young oriental female patients. However, a worldwide distribution is being recognized. Arterial stenosis represents the most frequently diagnosed manifestation. Progression of the flogistic process may lead to stenosis of the aorta and supraaortic vessels, compromising arterial circulation to the brain and upper limbs. Aneurysm presentation may also rarely occur. Based on a recently treated case, the authors report on the clinical presentation, concomitant inflammatory diseases, current diagnostic methods, and management of this disease.

Keywords

Takayasu disease Aortic aneurysm Aorta/aortic Cogan syndrome Inflammation Arteries 

Aortenaneurysma bei Patienten mit Takayasu-Arteriitis: Kasuistik

Zusammenfassung

Die Takayasu-Arteriitis (TA) ist eine unspezifische entzündliche Erkrankung des arteriellen Systems. Die Ätiologie ist unbekannt, obwohl verschiedene ätiopathogenetische Hypothesen formuliert wurden. Die Krankheit ist eine Form der Panarteriitis, beginnend mit einer Entzündung der Adventitia mit konsekutiver Einbindung der Media und Intima. Die Aorta und ihre Hauptäste sind meist an der Erkrankung beteiligt. Die Erkrankung wird am häufigsten bei jungen orientalischen weiblichen Patienten diagnostiziert, tritt jedoch weltweit auf. Eine arterielle Stenose stellt die am häufigsten diagnostizierte Manifestation dar. Im Verlauf des entzündlichen Prozesses kann es dann zu einer Stenosierung der Aorta und der supraaortalen Gefäße kommen, mit einer damit einhergehenden Beeinträchtigung der arteriellen Durchblutung des Gehirns und der oberen Extremitäten. Selten kann es im Verlauf der TA auch zu einem aortalen Aneurysma kommen. Ausgehend von einem kürzlich behandelten Fall berichten die Autoren über die klinische Präsentation, begleitende entzündliche Erkrankungen, aktuelle diagnostische Methoden und Management dieser Krankheit.

Schlüsselwörter

Takayasu-Arteriitis Aortenaneurysma Aorta/aortal Cogan-Syndrom Entzündung Arterien 
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Notes

Conflict of interest

The corresponding author states that there are no conflicts of interest.

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Copyright information

© Urban & Vogel, Muenchen 2011

Authors and Affiliations

  • S. Perrotta
    • 1
  • G. Rådberg
    • 1
  • A. Perrotta
    • 2
  • S. Lentini
    • 3
  1. 1.Department of Cardiothoracic SurgerySahlgrenska University HospitalGothenburgSweden
  2. 2.Department of PediatricsHospital“ A Cardarelli”CampobassoItaly
  3. 3.Department of Cardiothoracic SurgeryUniversity Hospital“G Martino”, University of MessinaMessinaItaly

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