Cellular and Molecular Life Sciences

, Volume 65, Issue 19, pp 2953–2956 | Cite as

Protein assemblies with palindromic structure motifs

  • N. Pinotsis
  • M. WilmannsEmail author
Visions & Reflections (Minireview)


Symmetric DNA sequence motifs allow the formation of palindromic protein/DNA complexes. Although symmetric protein sequence motifs are less common, recent structural discoveries have unraveled a few protein/protein complexes with palindromic symmetry. Remarkably, symmetric protein/protein complexes can be generated either by adjacent or remote sequence motifs, which may be repeated or inverted. This contribution reflects and comments on recent findings of palindromic protein/protein complexes.


Protein structure palindromic symmetry SH3 domain titin muscle 


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Copyright information

© Birkhaueser 2008

Authors and Affiliations

  1. 1.EMBL HamburgHamburgGermany
  2. 2.Section of Structural BiologyInstitute of Cancer Research, Chester Beatty LaboratoriesLondonUnited Kingdom

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