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Cellular and Molecular Life Sciences

, Volume 65, Issue 14, pp 2128–2137 | Cite as

Myosin I: From yeast to human

  • S. V. Kim
  • R. A. FlavellEmail author
Review

Abstract.

Myosin I is a non-filamentous, single-headed, actin-binding motor protein and is present in a wide range of species from yeast to man. The role of these class I myosins have been studied extensively in simple eukaryotes, showing their role in diverse processes such as actin cytoskeleton organization, cell motility, and endocytosis. Recently, studies in metazoans have begun to reveal more specialized functions of myosin I. It will be a major challenge in the future to examine the physiological functions of each class I myosin in different cell types of metazoans.

Keywords.

Myosin I actin vertebrate 

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Copyright information

© Birkhaueser 2008

Authors and Affiliations

  1. 1.Department of ImmunobiologyHoward Hughes Medical Institute, Yale University School of MedicineNew HavenUSA
  2. 2.The Helen L. and Martin S. Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular MedicineNew York University School of MedicineNew YorkUSA

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