Expression and function of galectin-1 in adult neural stem cells



Neural stem cells (NSCs) in the adult mammalian brain proliferate and continuously produce new neurons. To date, there has been little research into the functions of lectins in adult NSCs. Recently, we reported that a lectin, galectin-1, is expressed on adult NSCs and promotes their proliferation through its carbohydrate-binding ability. This evidence raises the possibility that glycans play roles in the proliferation of adult NSCs.


Lectin galectin neural stem cell glycan subventricular zone astrocyte 

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© Birkhäuser Verlag, Basel 2007

Authors and Affiliations

  1. 1.Department of PhysiologyKeio University School of MedicineTokyoJapan

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