Cellular and Molecular Life Sciences CMLS

, Volume 62, Issue 7–8, pp 824–833

Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines



During the last decade, a growing corpus of evidence has indicated an important role of inflammatory cytokines in the pathogenesis of cerebral lesion following stroke. Recent data suggest that genetics may in turn contribute to modulating the effects of inflammatory cytokines on cerebral infarction (CI). This paper reviews the physiologic characteristics of major inflammatory cytokines and recent research developments related to cell biology and pathobiology in CI. In particular, this review focuses on the genetic aspects of inflammatory cytokines and their implications in CI.

Key words.

Inflammatory cytokines pathogenesis stroke cerebral infarction gene polymorphisms 


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Copyright information

© Birkhäuser Verlag, Basel 2005

Authors and Affiliations

  1. 1.College of MedicineKyung Hee UniversityDongdaemun-Gu, SeoulSouth Korea
  2. 2.College of Oriental MedicineWonkwang UniversityIksan, JeonbukSouth Korea
  3. 3.Department of Oriental Pharmacy, College of PharmacyWonkwang UniversityIksan, JeonbukSouth Korea

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