Cellular and Molecular Life Sciences CMLS

, Volume 61, Issue 3, pp 281–291 | Cite as

Novel estrogen receptor coregulators and signaling molecules in human diseases

  • C. J. Barnes
  • R. K. Vadlamudi
  • R. KumarEmail author


The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

Estrogen receptor coregulators breast cancer signaling pathways chromatin remodeling 


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Copyright information

© Birkhäuser-Verlag Basel 2004

Authors and Affiliations

  1. 1.Department of Molecular and Cellular OncologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA

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