Advertisement

Cerebral Mycobacterium avium Infection in an HIV-Infected Patient Following Immune Reconstitution and Cessation of Therapy for Disseminated Mycobacterium avium Complex Infection

  • R. Murray
  • S. Mallal
  • C. Heath
  • M. French
Note

Abstract

 Reported here is a case of cerebral Mycobacterium avium complex infection that occurred in an HIV-infected patient, who had been treated for disseminated infection and had discontinued clarithromycin and ethambutol following a significant rise in his CD4+ T-cell count after starting highly active antiretroviral therapy. He responded well to excision of the lesion and reinstitution of multidrug therapy. Caution should be exercised when considering ceasing maintenance therapy for disseminated Mycobacterium avium complex infection in HIV-infected patients who demonstrate an apparently good immunologic response to highly active antiretroviral therapy, as this response may not necessarily restore protective immunity against all opportunistic pathogens.

Keywords

Immunologic Response Maintenance Therapy Clarithromycin Protective Immunity Significant Rise 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • R. Murray
    • 3
  • S. Mallal
    • 2
  • C. Heath
    • 1
  • M. French
    • 2
  1. 1.Department of Microbiology and Infectious Diseases, Royal Perth Hospital, Perth, Western Australia, AustraliaAU
  2. 2.Department of Clinical Immunology, Royal Perth Hospital, Perth, Western Australia, AustraliaAU
  3. 3.Department of Microbiology, Royal Darwin Hospital, PO Box 41326, Casuarina, Northern Territory 0811, Australia e-mail: ronanmurr@bigpond.com Tel.: +61-8-8922-7741 Fax: +61-8-8922-8843AU

Personalised recommendations