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Journal of Endocrinological Investigation

, Volume 11, Issue 10, pp 723–725 | Cite as

Fibrinogen and fibrinolytic activity in hyperthyroidism before and after antithyroid treatment

  • F. Marongiu
  • M. Conti
  • G. Mameli
  • M. L. Murtas
  • S. Balzano
  • G. Sorano
  • A. M. Mamusa
  • E. Martino
Short Communication

Abstract

Plasma concentration of fibrinogen and Bβ 15–42, a specific product of fibrinogen metabolism induced by plasmin, were measured in a group of patients with untreated hyperthyroidism and in controls. Significantly increased plasma levels of both parameters were observed in hyperthyroid patients. The restoration of euthyroidism either by antithyroid drug or by radioiodine caused a significant decrease of fibrinogen and Bβ15–42. These data indicate that hyperthyroidism is another clinical condition associated with increased concentration of fibrinogen and Bβ 15–42.

Key-words

Hyperthyroidism fibrinogen Bβ 15–42 

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Copyright information

© Italian Society of Endocrinology (SIE) 1988

Authors and Affiliations

  • F. Marongiu
    • 1
  • M. Conti
    • 1
  • G. Mameli
    • 1
  • M. L. Murtas
    • 2
  • S. Balzano
    • 2
  • G. Sorano
    • 1
  • A. M. Mamusa
    • 1
  • E. Martino
    • 2
  1. 1.Istituto di Medicina InternaCattedra di Clinica Medica IItaly
  2. 2.Cattedra di EndocrinologiaUniversità di CagliariCagliariItaly

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