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L’Endocrinologo

, Volume 4, Issue 2, pp 67–74 | Cite as

Androgeni: azioni biologiche, uso clinico e abuso nell’uomo

  • Giovanni Corona
  • Riccardo Mansani
  • Luisa Petrone
  • Mario Maggi
  • Gianni Forti
Article

Riassunto

Gli androgeni svolgono un ruolo importante in tutte le fasi della vita dell’uomo. Nell’adulto ipogonadico si assiste ad una riduzione della densità ossea, un aumento della massa grassa e una diminuzione della massa e della forza muscolare che vengono ripristinate dalla terapia sostitutiva. Una carenza androgenica si riflette negativamente anche sulla funzione sessuale e sulla libido. Non è possibile tuttavia stabilire la soglia critica di testosterone per una normale sessualità. Nonostante il largo utilizzo in ambito sportivo, solo negli ultimi anni sono stati chiariti i reali effetti derivanti dall’abuso di steroidi anabolizzanti in soggetti eugonadici. In particolare l’abuso di anabolizzanti, specie se associato ad un regime alimentare ed un programma di allenamento appropriati, determina un indiscusso vantaggio in alcune performance sportive come il sollevamento pesi o il lancio del disco, che richiedono una dimostrazione di massima forza volontaria. Più discusso è il loro ruolo in altre discipline sportive. Tali effetti sono comunque gravati da complicanze certe o potenziali che possono condizionare la comparsa di effetti secondari irreversibili o persino fatali che giustificano la campagna preventiva contro il loro utilizzo.

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Copyright information

© Springer International Publishing AG 2003

Authors and Affiliations

  • Giovanni Corona
    • 1
  • Riccardo Mansani
    • 1
  • Luisa Petrone
    • 1
  • Mario Maggi
    • 1
  • Gianni Forti
    • 1
  1. 1.Dipartimento di Fisiopatologia Clinica, Unità Operativa di AndrologiaUniversità degli Studi di FirenzeFirenzeItalia

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