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Journal of Endocrinological Investigation

, Volume 24, Issue 8, pp 564–569 | Cite as

Usefulness of endoscopic ultrasonography (EUS) in diagnosing esophageal infiltration of thyroid cancer

  • Akira OhshimaEmail author
  • H. Yamashita
  • S. Noguchi
  • S. Uchino
  • S. Watanabe
  • M. Toda
  • E. Koike
  • K. Takatsu
  • M. Inomata
  • T. Arita
Original Article

Abstract

Pre-operative evaluation of esophageal infiltration is sometimes difficult in patients with advanced thyroid cancer even with recent imaging modalities. We evaluated the accuracy of endoscopic ultrasonography (EUS) in diagnosing esophageal infiltration of thyroid cancer. Twenty-nine patients with advanced thyroid cancer underwent EUS and other imaging examinations before surgery. The diagnostic accuracy of EUS was compared with that of magnetic resonance imaging (MRI) and esophagography based on pathologic findings in 27 of the 29 cases. EUS clearly demonstrated the 5-layer structure of the esophageal wall. EUS detected cancer invasion into the muscularis propria of the esophagus correctly in 8 of 10 patients diagnosed pathologically with muscular infiltration. EUS was significantly more accurate than MRI and esophagography (88.9% vs 63.0% and 66.7%, respectively). The specificity of EUS was also significantly better than the specificities of MRI or esophagography (94.1% vs 58.8% and 64.7%, respectively). The sensitivity, positive predictive value and negative predictive value of EUS tended to be better than those of MRI and esophagography. EUS is useful in evaluating the esophageal infiltration of thyroid cancer. This method has the further advantage of detecting the exact depth of cancer invasion into the esophageal wall.

Key-words

Endoscopic ultrasonography thyroid cancer esophageal invasion 

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Copyright information

© Italian Society of Endocrinology (SIE) 2001

Authors and Affiliations

  • Akira Ohshima
    • 1
    Email author
  • H. Yamashita
    • 1
  • S. Noguchi
    • 1
  • S. Uchino
    • 1
  • S. Watanabe
    • 1
  • M. Toda
    • 1
  • E. Koike
    • 1
  • K. Takatsu
    • 1
  • M. Inomata
    • 2
  • T. Arita
    • 2
  1. 1.Noguchi Thyroid Clinic and Hospital FoundationBeppu, OitaJapan
  2. 2.Arita Gastro-intestinal HospitalOitaJapan

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