Aging Clinical and Experimental Research

, Volume 22, Issue 4, pp 330–339 | Cite as

A multi-dimensional questionnaire quantifying quality of life in elderly osteoporotic women: the Italian Triple-Q Osteoporosis Study

  • Dario Maggio
  • Carmelinda Ruggiero
  • Sara Ercolani
  • Maria Carmela Macchiarulo
  • Nicola Palmari
  • Filippo Luccioli
  • Sonia Andreani
  • Angela Mariani
  • Emanuela Costanzi
  • Antonio Cherubini
  • Maurizio Luchetti
  • Elena Zampi
  • Giuseppe Girasole
  • Gerolamo Bianchi
  • Maurizio Rossini
  • Chiara Cepollaro
  • Leonardo Sartori
  • Salvatore Minisola
  • Stefano Gonnelli
Original Article
First Online:
Received:
Accepted:

Abstract

Background and aims: In advanced age, the influence of vertebral fractures on quality of life extends well beyond the usual sequelae of osteoporosis. In order to intercept older subjects’ distress associated with the clinical, functional, social and psychological consequences of the disease, we developed and validated a multidimensional instrument (the triple-Q questionnaire) tailored to older women with osteoporotic fractures. We also examined specific aspects of the questionnaire correlated with bone mineral density. Methods: 100 osteoporotic women with vertebral fractures and 100 controls aged >65 years, underwent a thorough examination, which also included X-ray of the thoraco-lumbar spine, hip densitometry, the triple-Q questionnaire, and five referral instruments evaluating function, cognition, perception of general health, mood and pain. Results: The questionnaire was repeatable and able to discriminate between older women with and without vertebral fractures. There was a strong association between referral instrument scores and the corresponding single domain score of the questionnaire. Femoral BMD was also associated with scores indicating fear of falling, fear of fracture, and pain. Conclusions: The questionnaire intercepted the influence of osteoporosis on the quality of life of elderly women with vertebral fractures. Subjects who suffered from severe pain and were more fearful of falling were most likely to be severely osteoporotic.

Key words

Elderly osteoporosis quality of life scale vertebral fractures 
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References

  1. 1.
    Papaioannou A, Kennedy CC, Ioannidis G et al. Determinants of health-related quality of life in women with vertebral fractures. Osteoporos Int 2006; 3: 355–63.CrossRefGoogle Scholar
  2. 2.
    Atik OS, Gunal I, Korkusuz F. Burden of osteoporosis. Clin Orthop Relat Res 2006; 443: 19–24.PubMedCrossRefGoogle Scholar
  3. 3.
    Pfister AK, Welch CA, Lester MD, Emmett MK, Saville PD, Duerring SA. Cost-effectiveness strategies to treat osteoporosis in elderly women. South Med J 2006; 99: 123–31.PubMedCrossRefGoogle Scholar
  4. 4.
    Sinaki M. Musculoskeletal rehabilitation. In Riggs BL, Melton LJ III, Eds. Osteoporosis. Etiology, Diagnosis, and Management. New York: Raven Press, 1995: 435–73.Google Scholar
  5. 5.
    Lynn SG, Sinaki M, Westerlind KC. Balance characteristics of persons with osteoporosis. Arch Phys Med Rehabil 1997; 78: 273–7.PubMedCrossRefGoogle Scholar
  6. 6.
    Zimmerman SI, Fox KM, Magaziner J. Psychosocial aspects of osteoporosis. Phys Med Rehab Clin N Am 1995; 6: 441–53.Google Scholar
  7. 7.
    Lips P, Cooper C, Agnusdei D et al. for the Working Party for Quality of Life of the European Foundation for Osteoporosis. Quality of life as outcome in the treatment of osteoporosis: the development of a questionnaire for quality of life by the European Foundation for Osteoporosis. Osteoporos Int 1997; 7: 36–8.PubMedCrossRefGoogle Scholar
  8. 8.
    Lips P, Cooper C, Agnusdei D et al. for the Working Party for Quality of Life of the European Foundation for Osteoporosis. Quality of life in patients with vertebral fractures: validation of the Osteoporosis (QUALEFFO). Osteoporos Int 1999; 10: 150–60.PubMedCrossRefGoogle Scholar
  9. 9.
    Genant HK, Wu CY, Kuijk CV, Nevitt MC. Vertebral fracture assessment using a semi-quantitative technique. J Bone Miner Res 1993; 8: 1137–48.PubMedCrossRefGoogle Scholar
  10. 10.
    Pedrazzoni M, Girasole G, Bertoldo F et al. Definition of a population- specific DXA reference standard in Italian women: the Densitometric Italian Normative Study (DINS). Osteoporos Int 2003; 12: 978–82.CrossRefGoogle Scholar
  11. 11.
    Fillit HM, Picariello G. Practical Geriatric Assessment. London: Oxford University Press, 1998: 32–6.Google Scholar
  12. 12.
    Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34: 220–33.PubMedCrossRefGoogle Scholar
  13. 13.
    Rocca WA, Bonaiuto S, Lippi A et al. Validation of the Hodkinson Abbreviated Mental Test as a screening instrument for dementia in an Italian population. Neuroepidemiology 1992; 11: 288–95.PubMedCrossRefGoogle Scholar
  14. 14.
    Sheikh JL, Yesavage JA. Geriatric Depression Scale: recent evidence and development of a shorter version. In Brinf TL, Ed. Clinical Gerontology: A Guide to Assessment and Intervention. New York: Haworth Press, 1986: 165.Google Scholar
  15. 15.
    Caraceni A, Mendoza TR, Mencaglia E et al. A validation study of an Italian version of the Brief Pain Inventory (Breve Questionario per la Valutazione del Dolore). Pain 1996; 65: 87–92.PubMedCrossRefGoogle Scholar
  16. 16.
    Hall SE, Criddle RA, Comito TL, Prince RL. A case-control study of quality of life and functional impairment in women with long-standing vertebral osteoporotic fracture. Osteoporos Int 1999; 9: 508–15.PubMedCrossRefGoogle Scholar
  17. 17.
    Randell AG, Bhalerao N, Nguyen TV, Sambrook PM, Eisman JA, Silverman SL. Quality of life in osteoporosis: reliability, consistency, and validity of the osteoporosis assessment questionnaire. J Rheumatol 1998; 25: 1171–9.PubMedGoogle Scholar
  18. 18.
    Lyles KW, Gold DT, Shipp KM, Pieper CF, Martinez S, Mulhusen PL. Association of osteoporotic vertebral compression fractures with impaired functional status. Am J Med 1993; 94: 595–601.PubMedCrossRefGoogle Scholar
  19. 19.
    Ettinger B, Black DM, Nevitt MC et al. for the Study of Osteoporotic Fractures Research Group. Contribution of vertebral deformities to chronic back pain and disability. J Bone Miner Res 1992; 7: 449–56.PubMedCrossRefGoogle Scholar
  20. 20.
    Osteoporosis Quality of Life Study Group. Measuring quality of life in women with osteoporosis. Osteoporos Int 1997; 7: 478–87.CrossRefGoogle Scholar
  21. 21.
    Leech JA, Dulberg C, Kellie S, Patee L, Gay J. Relationship of lung function to severity of osteoporosis in women. Am Rev Respir Dis 1990; 141: 68–71.PubMedCrossRefGoogle Scholar
  22. 22.
    Lydick E, Zimmerman SI, Yawn B et al. Development and validation of a discriminative quality of life questionnaire for osteoporosis (the OPTQoL). J Bone Miner Res 1997; 12: 456–63.PubMedCrossRefGoogle Scholar
  23. 23.
    Helmes E, Hodsman A, Lazowski D et al. A questionnaire to evaluate disability in osteoporotic patients with vertebral compression fractures. J Gerontol 1995; 50A: M91–8.CrossRefGoogle Scholar
  24. 24.
    Cook DJ, Guyatt GH, Adachi JA et al. Quality of life issues in women with vertebral fractures due to osteoporosis. Arthr Rheum 1993; 6: 750–6.CrossRefGoogle Scholar

Copyright information

© Springer Internal Publishing Switzerland 2010

Authors and Affiliations

  • Dario Maggio
    • 1
  • Carmelinda Ruggiero
    • 1
  • Sara Ercolani
    • 1
  • Maria Carmela Macchiarulo
    • 1
  • Nicola Palmari
    • 1
  • Filippo Luccioli
    • 1
  • Sonia Andreani
    • 1
  • Angela Mariani
    • 1
  • Emanuela Costanzi
    • 1
  • Antonio Cherubini
    • 1
  • Maurizio Luchetti
    • 1
  • Elena Zampi
    • 1
  • Giuseppe Girasole
    • 2
  • Gerolamo Bianchi
    • 2
  • Maurizio Rossini
    • 3
  • Chiara Cepollaro
    • 4
  • Leonardo Sartori
    • 5
  • Salvatore Minisola
    • 6
  • Stefano Gonnelli
    • 7
  1. 1.Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Ospedale Santa Maria MisericordiaeUniversity of Perugia Medical SchoolS. Sisto PerugiaItaly
  2. 2.RheumatologyLa Colletta HospitalArenzanoItaly
  3. 3.Rheumatology Unit, Department of Biomedical and Surgical SciencesUniversity of VeronaItaly
  4. 4.Department of Internal MedicineUniversity of FlorenceItaly
  5. 5.Clinica Medica 1a, Department of Medical and Surgical SciencesUniversity of PadovaItaly
  6. 6.Department of Clinical Sciences, Policlinico Umberto IUniversity of Rome “La Sapienza”Italy
  7. 7.Department of Internal MedicineUniversity of SienaItaly

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