European Archives of Paediatric Dentistry

, Volume 11, Issue 2, pp 65–74 | Cite as

Treatment modalities in children with teeth affected by molar-incisor enamel hypomineralisation (MIH): A systematic review

Article

Abstract

AIM: This was to review the literature concerning the treatment of permanent teeth with molar-incisor hypomineralised enamel (MIH), comment about possible shortcomings and propose areas of future research. METHODS: A search of MedLine, Scopus, ResearchGate, Isis and Google Scholar databases was conducted using all terms relevant to the subject. Relevant papers published in English were identified after a review of their titles, abstracts or full reading of the papers. RESULTS: Of 189 references initially found, 66 papers were included; 34 directly relevant to the subject. From the latter, only 14 concerned laboratory or clinical studies dealing with treatment for MIH. Since 2000 11 reviews evaluated, to a certain extent, treatment options for affected teeth. Analysis of the proposed treatment modalities indicated options for prevention, restorations, and adhesion to hypomineralised enamel, full coronal coverage and extraction followed by orthodontics. Based on these findings, a treatment decision plan is proposed. CONCLUSIONS: Although treatment approaches for MIH have started to be clearer, long-term clinical trials, supported by laboratory studies, should be conducted to further facilitate the clinical management of this dental defect.

Key Words

molar incisor enamel hypomineralisation MIH treatment review 

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References

  1. Ashkenazi M, Sarnat H. Microabrasion of teeth with discoloration resembling hypomaturation enamel defects: four-year follow up. J Clin Pediatr Dent 2000;25(1):29–34.PubMedGoogle Scholar
  2. Al-Dobiyan F I, Shore R C, Duggal M S, Toumba K J. Elemental analyses of enamel of MIH molars compared to normal enamel. European Academy of Paediatric Dentistry Congress Abstract number O29. Eur Archs Paediatr Dent 2006;7:168.Google Scholar
  3. Alaluusua S. Aetiology of Molar-Incisor Hypomineralisation. A systematic review. Eur Archs Paediatr Dent 2010; 10:53–58Google Scholar
  4. American Academy of Paediatric Dentistry. Guideline on Paediatric Restorative Dentistry. Reference Manual 2008;163-169.Google Scholar
  5. American Academy of Paediatric Dentistry. Policy on the Use of Dental Bleaching for Children and Adolescents. Council on Clinical Affairs. 2009.Google Scholar
  6. Azarpazhooh A, Limeback H. Clinical efficacy of casein derivatives: a systematic review of the literature. J Am Dent Assoc. 2008;139(7):915–24.PubMedGoogle Scholar
  7. Bezerra AC, Leal SC, Otero SA, et al. Enamel opacities removal using two different acids: An in vivo comparison. J Clin Pediatr Dent. 2005;29(2):147–150.PubMedGoogle Scholar
  8. Cardenas Flores A, Flores Reyes H, Gordillo Moscoso A, et al. Clinical efficacy of 5% sodium hypochlorite for removal of stains caused by dental fluorosis. J Clin Pediatr Dent. 2009; 33(3):187–91.PubMedGoogle Scholar
  9. Chawla N, Messer LB, Silva M. Clinical Studies on Molar-Incisor-Hypomineralisation. Part1: Distribution and Putative Associations. Eur Archs Paediatr Dent 2008; 9(4):180–190.Google Scholar
  10. Croll TP. Restorative options for malformed permanent molars in children. Compend Contin Educ Dent. 2000;21:676–682.PubMedGoogle Scholar
  11. Dahl JE, Pallesen U. Tooth bleaching. A critical review of the biological aspects. Crit. Rev. Oral Biol. Med. 2003;14; 292.PubMedCrossRefGoogle Scholar
  12. Daly D, Waldron JM. Molar incisor hypomineralisation: clinical management of the young patient. J Ir Dent Assoc 2009;55(2): 83–86.PubMedGoogle Scholar
  13. European Academy of Paediatric Dentistry. Guidelines on the use of fluoride in children: an EAPD policy document. Eur Archs Paediatr Dent 2009;10:120–135.Google Scholar
  14. Fagrell TG, Lingström P, Olsson S, et al. Bacterial invasion of dentinal tubules beneath apparently intact but hypomineralized enamel in molar teeth with molar incisor hypomineralisation. Int J Paediatr Dent. 2008;18(5):333–40.PubMedCrossRefGoogle Scholar
  15. Fayle SA. Molar incisor hypomineralisation: restorative management. Eur J Paediatr Dent. 2003; 4:121–126.PubMedGoogle Scholar
  16. Fearne J, Anderson P, Davis G R. 3D X-ray microscopic study of the extent of variations in enamel density in first permanent molars with idiopathic enamel hypomineralisation. Br Dent J 2004; 196:634–638.PubMedCrossRefGoogle Scholar
  17. Fitzpatrick L, O’Connell A. First permanent molars with molar incisor hypomineralisation. J Ir Dent Assoc. 2007;53(1):32–7.PubMedGoogle Scholar
  18. Fleita D, Ali A, Alaluusua S. Molar-incisor hypomineralisation (MIH) in a group of school-aged children in Benghazi, Libya. Eur Archs Paediatr Dent. 2006;7(2):92–95.Google Scholar
  19. Harley KE, Ibbetson RJ. Dental anomalies — are adhesive castings the solution? Brit Dent J. 1993; 174(1):15–22.PubMedCrossRefGoogle Scholar
  20. Heijs S C, Dietz W, Noren J G, Blanksma N G, Jälevik B. Morhology and chemical composition of dentin in permanent first molars with the diagnose MIH. Swed Dent J 2007;31:155–164.PubMedGoogle Scholar
  21. Jälevik B, Noren J G. Enamel hypomineralisation of permanent first molars: a morphological study and survey of possible aetiological factors. Int J Paediatr Dent 2000;10:278–289.PubMedCrossRefGoogle Scholar
  22. Jälevik B, Odelius H, Dietz W, Noren J G. Secondary ion mass spectrometry and x-ray microanalysis of hypomineralised enamel in human permanent first molars. Arch Oral Biol 2001a;46:239–247.PubMedCrossRefGoogle Scholar
  23. Jälevik B, Klingberg G, Barregård L, Norén JG. The prevalence of demarcated opacities in permanent first molars in a group of Swedish children. Acta Odontol Scand 2001b;59:255–260.PubMedCrossRefGoogle Scholar
  24. Jälevik, B. Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralisation of their permanent first molars. Int J Paediatr Dent 2002; 12(1): 24–32.PubMedGoogle Scholar
  25. Jälevik B, Dietz W, Noren J G. Scanning electron micrograph analysis of hypomineralized enamel in permanent first molars. Int J Paediatr Dent 2005;15:233–240.PubMedCrossRefGoogle Scholar
  26. Jälevik B, Møller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralised permanent first molars. Int J Paediatr Dent 2007;17:328–335.PubMedCrossRefGoogle Scholar
  27. Jälevik B. Prevalence and Diagnosis of Molar-Incisor-Hypomineralisation (MIH). A systematic review. Eur Archs Paediatr Dent 2010; 10: 59–64Google Scholar
  28. Joiner A. The bleaching of teeth: A review of the literature. J Dent. 2006;34:412–419.PubMedCrossRefGoogle Scholar
  29. Koch MJ, Garcia-Godoy F. The clinical performance of laboratory-fabricated crowns placed on first permanent molars with developmental defects. J Am Dent Assoc 2000; 131(9): 1285–90.PubMedGoogle Scholar
  30. Kotsanos N, Kaklamanos EG, Arapostathis K. Treatment management of first permanent molars in children with Molar-Incisor Hypomineralisation. Eur J Paediatr Dent 2005;6(4):179–84.PubMedGoogle Scholar
  31. Leppaniemi A, Lukinmaa P-L, Alaluusua S. Nonfluoride Hypomineralisation in the permanent first molars and their impact on treatment need. Caries Res 2001;35:36–40.PubMedCrossRefGoogle Scholar
  32. Lygidakis NA, Chaliasou A, Siounas G. Evaluation of composite restorations in hypomineralised permanent molars: a four-year clinical trial. Eur J Paediatr Dent 2003;4(3):143–148.PubMedGoogle Scholar
  33. Lygidakis NA, Dimou G, Briseniou E. Molar-incisor hypomineralisation (MIH). Retrospective clinical study in Greek children. I. Prevalence and defect characteristics. Eur Archs Paediatr Dent 2008a;9:200–206.Google Scholar
  34. Lygidakis NA, Dimou G, Marinou D. Molar-Incisor-Hypomineralisation (MIH). A retrospective clinical study in Greek children. II. Possible medical aetiological factors. Eur Archs Paediatr Dent. 2008b; 9(4):207–17.Google Scholar
  35. Lygidakis NA, Dimou G, Stamataki E. Retention of fissure sealants using two different methods of application in children with hypomineralised molars (MIH): A 4 year clinical study. Eur Arch Paediatr Dent. 2009;10(4):223–6.PubMedCrossRefGoogle Scholar
  36. Mahoney EK. The treatment of localised hypoplastic and hypomineralized defects in first permanent molars. N Z Dent J. 2001;97(429):101–5.PubMedGoogle Scholar
  37. Mahoney EK, Rohanizadeh R, Ismail FSM, Kilpatrick NM, Swain MV. Mechanical properties and microstructure of hypomineralised enamel of permanent teeth. Biomaterials 2004;25:5091–5100.PubMedCrossRefGoogle Scholar
  38. Mathu-Muju K, Wright JT. Diagnosis and treatment of molar incisor hypomineralisation. Compend Contin Educ Dent 2006;27(11):604–10.PubMedGoogle Scholar
  39. Mejare I, Bergman E, Grindefjord M. Hypomineralized molars and incisors of unknown origin: treatment outcome at age 18 years. Int J Paediatr Dent 2005;15:20–28.PubMedCrossRefGoogle Scholar
  40. Muratbegovic A, Markovic N, Selinovic M G. Molar-Incisor-Hypomineralisation in Bosnia and Herzegovina: Prevalence, aetiology and clinical consequences in medium caries activity population. Eur Archs Paediatr Dent 2007;8:189–194.CrossRefGoogle Scholar
  41. Muratbegovic A, Zukanovic A, Markovic N. Molar-Incisor-Hypomineralisation impact on developmental defects of enamel prevalence in a low fluoridated area. Eur Archs Paediatr Dent 2008; 9(4):228–231.Google Scholar
  42. Peariasamy K, Anderson P, Brook AH. A quantitative study of the effect of pumicing and etching on the remineralisation of enamel opacities. Int J Paediatr Dent. 2001;11(3):193–200.PubMedCrossRefGoogle Scholar
  43. Peumans M, Van Meerbeek B, Lambrechts P, et al. The five-year clinical performance of direct composite additions to correct tooth form and position. Part I: aesthetic qualities. Clinical Oral Investigations 1997a;1:12–18.PubMedCrossRefGoogle Scholar
  44. Peumans M, Van Meerbeek B, Lambrechts P, et al. The five-year clinical performance of direct composite additions to correct tooth form and position. Part II: marginal qualities. Clinical Oral Investigations 1997b;1:19–26.PubMedCrossRefGoogle Scholar
  45. Rodd H D, Boissonade F M, Day P F. Pulpal status of hypomineralised permanent molars. Pediatr Dent 2007; 29: 514–520.PubMedGoogle Scholar
  46. Sapir S, Shapira J. Clinical solutions for developmental defects of enamel and dentin in children. Pediatr Dent 2007;29(4):330–6.PubMedGoogle Scholar
  47. Seddon JL. Extraction of four first molars: a case for a general practitioner? J Orthod 2004;31(2):80–85.PubMedCrossRefGoogle Scholar
  48. Seow WK, Amaratunge A. The effects of acid-etching on enamel from different clinical variants of amelogenesis imperfecta: an SEM study. Pediatr Dent 1998;0(1):37–42.Google Scholar
  49. Shen P, Cai F, Nowicki A, Vincent J, Reynolds E C. Remineralisation of enamel subsurface lesions by sugar-free chewing gum containing Casein Phosphopeptide-Amorphous calcium Phosphate. J Dent Res 2001;80:2066–2070.PubMedCrossRefGoogle Scholar
  50. Sign 50. A guideline developer’s handbook. http://www.sign.ac.uk/pdf/sign50.pdf
  51. Sundfeld RH, Croll TP, Briso AL, de Alexandre RS, Sundfeld Neto D. Considerations about enamel microabrasion after 18 years. Am J Dent. 2007;20(2):67–72.PubMedGoogle Scholar
  52. Thrash WJ, Dodds MW, Jones DL. The effect of stannous fluoride on dentinal hypersensitivity. Int Dent J 1994;44(Suppl 1):107–18.PubMedGoogle Scholar
  53. Venezie RD, Vadiakas G, Christensen JR, Wright JT. Enamel pretreatment with sodium hypochlorite to enhance bonding in hypocalcified amelogenesis imperfecta: case report and SEM analysis. Pediatr Dent 1994;6(6):433–6.Google Scholar
  54. Wakiaga J, Brunton P, Silikas N, Glenny AM. Direct versus indirect veneers for intrinsic dental stains. Cochrane database of systematic reviews. 2004 issue 1.Google Scholar
  55. Weerheijm KL, Jälevik B, Alaluusua S. Molar-Incisor Hypomineralisation. Caries Res 2001;35:390–1.PubMedCrossRefGoogle Scholar
  56. Weerheijm KL, Duggal M, Mejare I, et al. Judgement criteria for Molar-Incisor-Hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur Archs Paediatr Dent 2003;3:110–113.Google Scholar
  57. Weerheijm KL. Molar incisor hypomineralisation (MIH): clinical presentation, aetiology and management. Dent Update 2004;31(1): 9–12.PubMedGoogle Scholar
  58. Welbury RR. A clinical study of a microfilled composite resin for labial veneers. IntJ Paediatr Dent 1991;1:9–15.CrossRefGoogle Scholar
  59. William V, Messer LB, Burrow MF. Molar incisor hypomineralisation: review and recommendations for clinical management. Pediatr Dent 2006a;28(3):224–32.PubMedGoogle Scholar
  60. William V, Burrow MF, Palamara JE, et al. Microshear bond strength of resin composite to teeth affected by molar hypomineralisation using 2 adhesive systems. Pediatr Dent 2006b;28:233–41.PubMedGoogle Scholar
  61. Williams JK, Gowans AJ. Hypomineralised first permanent molars and the orthodontist. Eur J Paediatr Dent 2003;4:129–132.PubMedGoogle Scholar
  62. Willmott NS, Bryan RA, Duggal MS. Molar-incisor-hypomineralisation: a literature review. Eur Archs Paediatr Dent. 2008;9(4): 172–9.Google Scholar
  63. Wong FSL, Winter GB. Effectiveness of microabrasion technique for improvement of dental aesthetics. Br Dent J. 2002;193(3):155–158.PubMedCrossRefGoogle Scholar
  64. Wray A, Welbury R. Treatment of intrinsic discoloration in permanent anterior teeth in children and adolescents. UK National Clinical guidelines in Paediatric Dentistry. IntJ Paediatr Dent 2001;11:309–315.CrossRefGoogle Scholar
  65. Wright JT. The etch-bleach-seal technique for managing stained enamel defects in young permanent incisors. Pediatr Dent 2002;24:249–252.PubMedGoogle Scholar
  66. Zagdwon AM, Fayle SA, Pollard MA. A prospective clinical trial comparing preformed metal crowns and cast restorations for defective first permanent molars. Eur J Paediatr Dent 2003;4:138–142.PubMedGoogle Scholar

Copyright information

© Adis International 2010

Authors and Affiliations

  1. 1.Dept of Paediatric DentistryCommunity Dental Centre for ChildrenAthensGreece

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