Respiratory medicine is a vast and evolving area for researchers, primary care physicians and specialists. To help keep you up-to-date with the latest advances worldwide on all aspects of drug therapy and management of respiratory disorders, this section of the journal brings you information selected from the drug therapy reporting service Inpharma Weekly 1. The following reports are selected from the latest issues, summarizing the most important research and development news, clinical studies, treatment guidelines, pharmacoeconomic and adverse reaction news, and expert opinion pieces published across a broad range of literature sources.
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1 Inpharma Weekly provides rapid alerts to news on drugs and drug therapy. Summarizing information selected form over 1600 biomedical journals, this newsletter is produced by Adis International and is available in a variety of formats. Please contact your nearest Adis office for subscription details. reports, recently published in the European Respiratory Journal.[1,2]
Wolter J, Seeney S, Bell S, et al. Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial. Thorax 2002; 57: 212–6
Peckham DG. Macrolide antibiotics and cystic fibrosis: do the macrolides have a role in the treatment of cystic fibrosis? Thorax 2002; 57: 189–90
Vincken W, van Noord JA, Greefhorst APM, et al. Improved health outcomes in patients with COPD during 1 yr’s treatment with tiotropium. Eur Resp J 2002; 19: 209–16
Casaburi R, Mahler DA, Jones PW, et al. A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease. Eur Resp J 2002; 19: 217–24
Rees PJ. Tiotropium in the management of chronic obstructive pulmonary disease. Eur Resp J 2002; 19:205–6
Eid N, Morton R, Olds B, et al. Decreased morning serum Cortisol levels in children with asthma treated with inhaled fluticasone propionate. Pediatrics 2002; 109 (Pt 1): 217–21
Maltais F, Ostinelli J, Bourbeau J, et al. Comparison of nebulized budesonide and oral prednisolone with placebo in the treatment of acute exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial. Am J Resp Crit Care Med 2002; 165: 698–703
Brown ES, Suppes T, Khan DA, et al. Mood changes during prednisone bursts in outpatients with asthma. J Clin Psychopharmacol 2002; 22: 55–61
Ollendorf DA, Pozniak AS, Bowers BW, et al. An economic analysis of alternative step-up therapies in asthma patients receiving inhaled corticosteroids. P & T 2002; 27: 147–53
Ohio State University. Common asthma drug saves patients money, trips to hospital [online]. Media release: [3 pages]. Available from URL: http://www.osu.edu [Accessed 2002 Apr 11]
Paramothayan S, Jones PW. Corticosteroid therapy in pulmonary sarcoidosis: a systematic review. JAMA 2002; 287: 1301–7
Pearlman DS, White MV, Lieberman AK, et al. Fluticasone propionate/salmeterol combination compared with montelukast for the treatment of persistent asthma. Ann Allergy Asthma Immunol 2002; 88: 227–35
Inpharma Weekly provides rapid alerts to news on drugs and drug therapy. Summarizing information selected form over 1600 biomedical journals, this newsletter is produced by Adis International and is available in a variety of formats. Please contact your nearest Adis office for subscription details.