Molecular Diagnosis & Therapy

, Volume 14, Issue 4, pp 215–222

Human Papillomavirus DNA Testing for Cervical Cancer Screening

Practical Aspects in Developing Countries
Review Article

DOI: 10.1007/BF03256376

Cite this article as:
Belinson, S.E. & Belinson, J.L. Mol Diag Ther (2010) 14: 215. doi:10.1007/BF03256376


Cervical cancer is the second most common cancer in women worldwide, and the most common cause of death from cancer in women in the developing world. Cervical cancer represents the only gynecologic cancer that can be prevented through regular screening. Although there are established screening programs in the Western world that have effectively reduced the burden of cervical cancer, these programs have relied on insensitive screening technologies that depend on the long preinvasive phase of cervical carcinogenesis. The developing world faces specific additional challenges in implementing a successful cervical cancer screeing program.

The association between cervical cancers and human papillomavirus (HPV) make testing for the presence of HPV DNA a valuable screening tool. This review focuses on practical aspects of the implementation and delivery of HPV testing as the primary cervical cancer screening strategy in the developing world, and attempts to offer some solutions to the real-world challenges faced in these regions.

Copyright information

© Adis Data Information BV 2010

Authors and Affiliations

  1. 1.Preventive Oncology International, Inc.Cleveland HeightsUSA

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