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Pyrazoles as building blocks in heterocyclic synthesis: Synthesis of pyrazolo [3,4-d]pyrimidine, pyrazolo[3,4-e][1,4]diazepine, pyrazolo [3,4-d][1,2,3]triazine and pyrolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives

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Abstract

Several new pyrazolo[3,4-d]pyrimidine, pyrazolo[3,4-e][1,4]diazepine, pyrazolo[3,4-d][1,2,3]triazine and pyrolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives were prepared by the reaction of the corresponding 5-amino-pyrazole-4-carbonitrile derivative with different organic reagents under different reaction conditions. Using IR, 1H NMR, and mass spectra we have characterized all new compounds.

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Correspondence to A. -F. A. Harb.

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Harb, A.-.A., Abbas, H.H. & Mostafa, F.H. Pyrazoles as building blocks in heterocyclic synthesis: Synthesis of pyrazolo [3,4-d]pyrimidine, pyrazolo[3,4-e][1,4]diazepine, pyrazolo [3,4-d][1,2,3]triazine and pyrolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives. JICS 2, 115–123 (2005). https://doi.org/10.1007/BF03247202

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Keyword

  • Pyrazolo[3,4-d]pyrimidine
  • Pyrazolo[3,4-e][1,4]diazepine
  • Pyrazolo[3,4-d][1,2,3]-triazine
  • Pyrolo[4,3-e][1,2,4] diazole[1,5-a]pyrimidine
  • IR
  • 1H NMR