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Cyanuric chloride catalysed rapid conversion of β-ketoesters into β-enaminoesters under mild and solvent-free conditions

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Abstract

Cyanuric chloride is shown to be an extremely efficient catalyst for the synthesis of β-enaminoesters from β-ketoesters under solvent-free conditions by grinding in a mortar with pestle at 25 °C. A short reaction time, an inexpensive and easily available catalyst, mild reaction conditions and excellent yields of the products are attractive features of this methodology.

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Correspondence to V. T. Kamble.

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Kamble, V.T., Joshi, N.S. & Atkore, S.T. Cyanuric chloride catalysed rapid conversion of β-ketoesters into β-enaminoesters under mild and solvent-free conditions. JICS 8, 616–621 (2011). https://doi.org/10.1007/BF03245892

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Keywords

  • Amines
  • β-Enaminoesters
  • β-Ketoesters
  • Cyanuric chloride