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Whey protein

Effects on insulin secretion and intestinal health via intestinal peptides

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Summary

Ingestion of whey protein has been shown to promote satiety, stimulate insulin release and maintain digestive health. These beneficial effects are linked with stimulation of intestinal proglucagon-derived peptides and rapid digestion and absorption of amino acids from whey protein into the bloodstream. Functional foods that incorporate whey protein may provide health benefits for individuals at risk for obesity and type 2 diabetes, as well as those with intestinal diseases. The ability of whey protein or whey protein hydrolysate to improve glucose homeostasis and promote healing of the intestinal mucosa is associated with decreased degradation of intestinal peptides via modulation of dipeptidyl peptidase-IV activity in animal models. Further research in human subjects and animal models is needed to more fully understand the effects of whey protein on intestinal physiology and the regulation of glucose and insulin homeostasis.

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Correspondence to Denise M. Ney.

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Ney, D.M., Boehler, C.J. Whey protein. Nutrafoods 10, 17–22 (2011). https://doi.org/10.1007/BF03223384

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Keywords

  • Whey proteins
  • Intestinal Peptides
  • Glycemia
  • Insulinemia