In subjects with familial hypercholesterolemia cholesterol absorption efficiency was insignificantly reduced during a short-term more consistently during long-term pravastatin treatment. A cholesterol feeding had no effect on LDL cholesterol level but reduced absorption efficiency during a long-term lovastatin treatment.
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Miettinen, T.A. Inhibition of cholesterol absorption by HMG-CoA reductase inhibitor. Eur J Clin Pharmacol 40, S19–S21 (1991). https://doi.org/10.1007/BF03216283
- methyl sterols
- cholesterol absorption
- LDL cholesterol
- dietary cholesterol