In the present study the amount of protection offered by the use of S-phenetyl formamidino 4(N-ethyl isothioamide) morpholine dihydrochloride to adrenal gland was investigated on albino rats against two graded doses of x-rays (1500R each). Total body x-irradiation brought about the hypertrophy and degranulation of adrenal cortical and medullary cells. The extent of hypertrophy and degranulation increased after the 2nd exposure to x-rays. Treatment with S-phenetyl formamidino 4(N-ethyl isothioamide) morpholine dihydrochloride prior to each dose of irradiation precluded the radiation changes caused in the adrenal cortex and medulla of the rats.
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Chaturvedi, P.K., Hasan, S.S. Effect of two graded doses of x-irradiation on the rat adrenal gland and its protection by S-phenetyl formamidino 4(N-ethyl isothioamide) morpholine dihydrochloride. Proc Ani Sci 94, 523–526 (1985). https://doi.org/10.1007/BF03186362
- S-phenetyl formamidino 4(N-ethyl isothioamide) morpholine dihydrochloride
- adrenal gland