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Evolutionary status ofEntamoeba

Abstract

In addition to its medical importance as parasitic pathogen,Entamoeba has aroused people’s interest in its evolutionary status for a long time. Lacking mitochondrion and other intracellular organelles common to typical eukaryotes,Entamoeba and several other amitochondrial protozoans have been recognized as ancient premitochondriate eukaryotes and named “archezoa”, the most primitive extant eukaryotes. It was suggested that they might be living fossils that remained in a primitive stage of evolution before acquisition of organelles, lying close to the transition between prokaryotes and eukaryotes. However, recent studies revealed thatEntamoeba contained an organelle, “crypton” or “mitosome”, which was regarded as specialized or reductive mitochondrion. Relative molecular phylogenetic analyses also indicated the existence or the probable existence of mitochondrion inEntamoeba. Our phylogenetic analysis based on DNA topoisomerase II strongly suggested its divergence after some mitchondriate eukaryotes. Here, all these recent researches are reviewed and the evolutionary status ofEntamoeba is discussed.

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Author information

Correspondence to Jianfan Wen.

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Cite this article

Dong, J., Wen, J., Xin, D. et al. Evolutionary status ofEntamoeba . Chin.Sci.Bull. 49, 1847–1853 (2004). https://doi.org/10.1007/BF03183412

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Keywords

  • Entamoeba
  • mitochondrion
  • mitosome
  • molecular phylogenetic analyses
  • evolutionary status