The clinical application of PET/CT: a contemporary review

  • Z. Brady
  • M. L. Taylor
  • M. Haynes
  • M. Whitaker
  • A. Mullen
  • L. Clews
  • M. Partridge
  • R. J. Hicks
  • J. V. Trapp
Review Article

Abstract

The combination of positron emission tomography (PET) scanners and x-ray computed tomography (CT) scanners into a single PET/CT scanner has resulted in significant improvements in the diagnosis and staging of disease, particularly in the field of oncology. A decade on from the publication of the details of the first PET/CT scanner, we review the technology and applications of the modality. We examine the design aspects of combining two different imaging types into a single scanner, and the artefacts produced such as attenuation correction, motion and CT truncation artefacts. The article also provides a discussion and literature review of the applications of PET/CT to date, covering detection of tumours, radiotherapy treatment planning, patient management, and applications external to the field of oncology.

Key words

PET/CT applications oncology treatment planning 

Copyright information

© Australasian College of Physical Scientists and Engineers in Medicine 2008

Authors and Affiliations

  • Z. Brady
    • 1
    • 2
  • M. L. Taylor
    • 2
    • 3
  • M. Haynes
    • 2
    • 3
  • M. Whitaker
    • 2
    • 4
  • A. Mullen
    • 2
    • 5
  • L. Clews
    • 2
    • 6
  • M. Partridge
    • 7
  • R. J. Hicks
    • 5
  • J. V. Trapp
    • 8
  1. 1.Radiology DepartmentThe Alfred HospitalPrahranAustralia
  2. 2.Applied PhysicsRMIT UniversityMelbourneAustralia
  3. 3.William Buckland Radiotherapy Centre (WBRC)The Alfred HospitalPrahranAustralia
  4. 4.Royal Prince Alfred HospitalCamperdownAustralia
  5. 5.Peter MacCallum Cancer CentreAustralia
  6. 6.Calvary Mater NewcastleWarratahAustralia
  7. 7.Joint Department of PhysicsThe Institute of Cancer ResearchSuttonUK
  8. 8.School of Physical and Chemical SciencesQUTBrisbaneAustralia

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