Nuclear oxidation in the flavone series

Part VII. Oxidation of baicalein and scutellarein
  • V. V. Sreerama Murti
  • K. Visweswara Rao
  • T. R. Seshadri


Nuclear oxidation of baicalein and scutellarein takes place readily in the 8-position, the partial methyl ethers being employed. Further methylation yields fully methylated ethers of the nobiletin series and demethylation the corresponding nor-compounds. For purposes of comparison these substances have also been prepared from 2∶5-dihydroxy-3∶4∶6-trimethoxy acetophenone by the Allan-Robinson method. The characteristic properties and reactions of these compounds are described.


Baicalein Chrysin Aqueous Sodium Hydroxide Nobiletin Oroxylin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Rajagopalan, Rao and SeshadriProc. Ind. Acad. Sci., A, 1947,26, 18.Google Scholar
  2. 2.
    BakerJ. C. S., 1941, 650.Google Scholar
  3. 3.
    HoriiJ. Pharm. Soc. Japan, 1940,60, 614;Brit. Chem. Abs., A, II, 1941, 381.Google Scholar
  4. 4.
    BargelliniC. A., 1920, 1527.Google Scholar

Copyright information

© Indian Academy of Sciences 1947

Authors and Affiliations

  • V. V. Sreerama Murti
    • 1
  • K. Visweswara Rao
    • 1
  • T. R. Seshadri
    • 1
  1. 1.Department of ChemistryAndhra UniversityWaltair

Personalised recommendations