Diabetologia

, 40:B44 | Cite as

Beta-cell replacement

  • N. M. Desai
  • G. S. Korbutt
  • C. F. Barker
  • K. J. Lafferty
Article
  • 209 Downloads

Keywords

Islet Transplantation IDDM Patient Insulin Independence Hyperacute Rejection Islet Allograft 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977–986CrossRefGoogle Scholar
  2. 2.
    Reckard CR, Ziegler MM, Barker CF (1973) Physiological and immunological consequences of transplanting isolated pancreatic islets. Surgery 74: 91–99PubMedGoogle Scholar
  3. 3.
    Sollinger HW, Ploeg RJ, Eckhoff DE et al. (1993) Two hundred consecutive simultaneous pancreas-kidney transplants with bladder drainage. Surgery 114: 736–743PubMedGoogle Scholar
  4. 4.
    Hering BJ, Brendel MD, Schultz AO, Schultz B, Bretzel RG (1996) International islet transplant registry. Newsletter 6: 1–20Google Scholar
  5. 5.
    Ricordi C, Karatzas T, Nery J et al. (1997) High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing. Transplantation 63: 7–11CrossRefPubMedGoogle Scholar
  6. 6.
    Lau HT, Yu M, Fontana A, Stoeckert CJ (1996) Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science 273: 109–112CrossRefPubMedGoogle Scholar
  7. 7.
    Korbutt GS, Elliot JF, Rajotte RV (1997) Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression. Diabetes 46: 317–322CrossRefPubMedGoogle Scholar
  8. 8.
    Posselt AM, Barker CF, Tomaszewski JE, Markmann JF, Choti MA, Naji A (1990) Induction of donor-specific unresponsiveness by intrathymic islet transplantation. Science 249: 1293–1295CrossRefPubMedGoogle Scholar
  9. 9.
    Stegall MD, Lafferty KJ, Kam I, Gill RG (1996) Evidence of recurrent autoimmunity in human allogeneic islet transplantation. Transplantation 61: 1272–1274CrossRefPubMedGoogle Scholar
  10. 10.
    Groth CG, Korsgren O, Tibell A et al. (1994) Transplantation of porcine fetal pancreas to diabetic patients. Lancet 344: 1402–1404CrossRefPubMedGoogle Scholar
  11. 11.
    Patience C, Takeuchi Y, Weiss RA (1997) Infection of human cells by an endogenous retrovirus of pigs. Nature Medicine 3: 282–286CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • N. M. Desai
    • 1
  • G. S. Korbutt
    • 2
  • C. F. Barker
    • 1
  • K. J. Lafferty
    • 3
  1. 1.Department of SurgeryUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.Surgical-Medical Research InstituteUniversity of AlbertaEdmontonCanada
  3. 3.John Curtin School of Medical ResearchCanberraAustralia

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