Annals of Nuclear Medicine

, Volume 11, Issue 4, pp 335–338

Discordant splenic uptake of Tc-99m colloid and Tc-99m denatured RBC in candidiasis-endocrinopathy syndrome

  • Tamio Aburano
  • Ryuji Katada
  • Noriyuki Shuke
  • Wakako Yamamoto
  • Takako Kawakami
  • Isao Makino
  • Junichi Sato
  • Yukio Ishikawa
Case Report

Abstract

We report discordant splenic uptake of Tc-99m colloid and Tc-99m heat-denatured red blood cells (RBC) which occurred in a 21-year-old female with candidiasis-endocrinopathy syndrome. Tc-99m colloid liver-spleen imaging showed no splenic uptake, suggesting the presence of functional asplenia. A subsequent Tc-99m heat-denatured RBC study clearly revealed a small spleen with preserved sequestrating function. These results may demonstrate that the qualitative dissociation of splenic functions in processing colloid and denatured RBC in functional asplenia: the sequestration function remains while the reticuloendothelial system is impaired.

Key words

Tc-99m colloid Tc-99m denatured RBC imaging functional asplenia candidiasis-endocrinopathy syndrome 

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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • Tamio Aburano
    • 1
  • Ryuji Katada
    • 1
  • Noriyuki Shuke
    • 1
  • Wakako Yamamoto
    • 1
  • Takako Kawakami
    • 2
  • Isao Makino
    • 2
  • Junichi Sato
    • 3
  • Yukio Ishikawa
    • 3
  1. 1.Department of RadiologyAsahikawa Medical CollegeAsahikawaJapan
  2. 2.Second Department of Internal MedicineAsahikawa Medical College HospitalJapan
  3. 3.Radiological ServiceAsahikawa Medical College HospitalJapan

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