Huisarts en Wetenschap

, Volume 46, Issue 13, pp 102–106 | Cite as

Fenomeen van Raynaud en wintertenen

  • V van der Meer
  • LC de Jong-Potjer
  • JAH Eekhof
  • A Knuistingh Neven
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Samenvatting

Verkleurde pijnlijke vingers of tenen bij lage omgevingstemperatuur, dat zijn de kenmerkende verschijnselen van het fenomeen van Raynaud (FR) en wintertenen. Prevalentiecijfers van FR variëren van 5% tot 21% afhankelijk van geografische variatie, sekse en definitie.

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Literatuur

  1. Hildegard MR, Carpentier PH, Weinrich MC, Keil JE, Franco A, Drouet P, et al. Geographic variation in the prevalence of Raynaud's phenomenon: Charleston, SC, USA vs Tarentaise, Savoie, France. J Rheumatol 1993;20:70-6.Google Scholar
  2. Silman A, Holligan S, Brennan P, Maddison P. Prevalence of symptoms of Raynaud's phenomenon in general practise. BMJ 1990;301:590-2.CrossRefPubMedGoogle Scholar
  3. Freedman RR, Dayes MD. Familial aggregation of primary Raynaud's disease. Arthritis Rheum 1996;39:1189-1201.CrossRefPubMedGoogle Scholar
  4. Okkes IM, Oskam SK, Lamberts H. Van klacht naar diagnose. Episodegegevens uit de huisartspraktijk. Boek met CD-ROM. Bussum: Coutinho, 1998.Google Scholar
  5. Ong RSG, De Waal MWM. RHUH-LEO basisrapport X: databestand 2000/2001. Leiden: LUMC Afdeling Huisartsgeneeskunde en Verpleeghuisgeneeskunde, 2002.Google Scholar
  6. Wigley FM. Raynaud's phenomenon. N Engl J Med 2002;347:1001-8.CrossRefPubMedGoogle Scholar
  7. Block JA, Sequeira W. Raynaud's phenomenon. Lancet 2001;357: 2042-8.CrossRefPubMedGoogle Scholar
  8. Van Leusden HAIM, redactie. Diagnostisch Kompas 1999/2000. Amstelveen: Commissie Aanvullende Diagnostiek van het College voor Zorgverzekeringen, 1999.Google Scholar
  9. LeRoy EC, Medsger TA Jr. Raynaud's phenomenon: a proposal for classification. Clin Exp Rheumatol 1992;10:485-8.PubMedGoogle Scholar
  10. Spencer-Green G. Outcomes in primary Raynaud phenomenon: a meta-analysis of the frequency, rates, and predictors of transition to secondary disease. Arch Intern Med 1998;158:595-600.CrossRefPubMedGoogle Scholar
  11. Goette DK. Chilblains (periones). J Am Acad Dermatol 1990;23:257- 62.CrossRefPubMedGoogle Scholar
  12. Freedman RR, Baer RP, Mayes MD. Blockade of vasospastic attacks by alpha 2-adrenergic but not alpha 1-adrenergic antagonists in idiopathic Raynaud's disease. Circulation 1995;92:1448-9.PubMedGoogle Scholar
  13. Susol E, MacGregor AJ, Barrett JH, Wilson H, Black C, Welsh K, Silman A, et al. A two-stage, genome-wide screen for susceptibility loci in primary Raynaud's phenomenon. Arthritis Rheum 2000;43:1641-6.CrossRefPubMedGoogle Scholar
  14. Carruthers R. Chilblains (perniones). Aust Fam Physician 1988;17: 968-9.PubMedGoogle Scholar
  15. Smilde TJ, Wollersheim H. Therapeutische (on)mogelijkheden bij het fenomeen van Raynaud. Ned Tijdschr Geneeskd 1996;140:352-7.PubMedGoogle Scholar
  16. Raynaud's treatment study investigators. Comparison of sustainedrelease nifedipine and temperature biofeedback for treatment of primary Raynaud's phenomenon: results from a randomized clinical trial with 1-year follow-up. Arch Intern Med 2000;160:1101-8.Google Scholar
  17. Challenor VF, Waller DG, Hayward RA, Griffin MJ, Roath OS. Vibrotactile sensation and response to nifedipine dose titration in primary Raynaud's phenomenon. Angiology 1989;40:122-8.CrossRefPubMedGoogle Scholar
  18. Sarkozi J, Bookman AA, Mahon W, Ramsay C, Detsky AS, Keystone EC. Nifedine in the treatment of idiopathic Raynaud's syndrome. J Rheumatol 1986;13:331-6.PubMedGoogle Scholar
  19. Gjorup T, Kelbaek H, Hartling OJ, Nielsen SL. Controlled doubleblind trial of the clinical effect of nifedipine in the treatment of idiopathic Raynaud's phenomenon. Am Heart J 1986;111:742-5.CrossRefPubMedGoogle Scholar
  20. Corbin DO, Wood DA, Macintyre CC, Housley E. A randomized double blind cross-over trial of nifedipine in the treatment of primary Raynaud's phenomenon. Eur Heart J 1986;7:165-70.PubMedGoogle Scholar
  21. Ferri C, Cecchetti R, Cini G, Gambini I, La Civita L, Bernini L, et al. Slow-releasing nicardipine in the treatment of Raynaud's phenomenon without underlying diseases. Clin Rheumatol 1992;11:76-80.CrossRefPubMedGoogle Scholar
  22. Controlled multicenter double-blind trial of nicardipine in the treatment of primary Raynaud phenomenon. French Cooperative Multicenter Group of Raynaud Phenomenon, Paris, France. Am Heart J 1991;122:352-5.Google Scholar
  23. Kallenberg CG, Wouda AA, Mems L, Wesseling H. Once daily felodipine in patients with primary Raynaud's phenomenon. Eur J Clin Pharmacol 1991;40:313-5.CrossRefPubMedGoogle Scholar
  24. Leppert J, Jonasson T, Nilsson H, Ringqvist I. The effect of isradipine, a new calcium-channel antagonist, in patients with primary Raynaud's phenomenon: a single-blind dose-response study. Cardiovasc Drugs Ther 1989;3:397-401.CrossRefPubMedGoogle Scholar
  25. Gjorup T, Hartling OJ, Kelbaek H, Nielsen SL. Controlled double blind trial of nisoldipine in the treatment of idiopathic Raynaud's phenomenon. Eur J Clin Pharmacol 1986;31:387-9.CrossRefPubMedGoogle Scholar
  26. Thompson AE, Shea B, Welch V, Fenlon D, Pope JE. Calcium-channel blockers for Raynaud's phenomenon in systemic sclerosis. Arthritis Rheum 2001;44:1841-7.CrossRefPubMedGoogle Scholar
  27. Nielsen SL, Vitting K, Rasmussen K. Prazosin treatment of primary Raynaud's phenomenon. Eur J Clin Pharmacol 1983;24:421-3.CrossRefPubMedGoogle Scholar
  28. Wollersheim H, Thien T, Fennis J, Van Elteren P, Van ’t Laar A. Double-blind, placebo-controlled study of prazosin in Raynaud's phenomenon. Clin Pharmacol Ther 1986;40:219-25.PubMedGoogle Scholar
  29. Surwit RS, Allen LM 3rd, Gilgor RS, Duvic M. The combined effect of prazosin and autogenic training on cold reactivity in Raynaud's phenomenon. Biofeedback Self Regul 1982;7:537-44.CrossRefPubMedGoogle Scholar
  30. Pope J, Fenlon D, Thompson A, Shea B, Furst D, Wells G, et al. Prazosin for Raynaud's phenomenon in progressive systemic sclerosis (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software.Google Scholar
  31. Pope J, Fenlon D, Thompson A, Shea B, Furst D, Wells G, et al. Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software.Google Scholar
  32. Dziadzio M, Denton CP, Smith R, Howell K, Blann A, Bowers E, et al. Losartan therapy for Raynaud's phenomenon and scleroderma: clinical and biochemical findings in a fifteen-week, randomized, parallelgroup, controlled trial. Arthritis Rheum 1999;42:2646-55.CrossRefPubMedGoogle Scholar
  33. Pancera P, Sansone S, Secchi S, Covi G, Lechi A. The effects of thromboxane A2 inhibition (picotamide) and angiotensin II receptor blockade (losartan) in primary Raynaud's phenomenon. J Intern Med 1997;242:373-6.CrossRefPubMedGoogle Scholar
  34. Coleiro B, Marshall SE, Denton CP, Howell K, Blann A, Welsh KI, Black CM. Treatment of Raynaud's phenomenon with the selective serotonin reuptake inhibitor fluoxetine. Rheumatology 2001;40:1038- 43.CrossRefPubMedGoogle Scholar
  35. Denton CP, Howell K, Stratton RJ, Black CM. Long-term low molecular weight heparin therapy for severe Raynaud's phenomenon: a pilot study. Clin Exp Rheumatol 2000;18:499-502.PubMedGoogle Scholar
  36. Leh LS, Manning J, More T, Tully MP, O'Reilly D, Jayson MI. Sustained-release transdermal glyceryl trinitrate patches as a treatment for primary and secondary Raynaud's phenomenon. Br J Rheumatol. 1995;34:636-41.CrossRefGoogle Scholar
  37. Rustin MH, Newton JA, Smith NP, Dowd PM. The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial. Br J Dermatol 1989;120:267-75.CrossRefPubMedGoogle Scholar

Copyright information

© Bohn Stafleu van Loghum 2003

Authors and Affiliations

  • V van der Meer
    • 1
  • LC de Jong-Potjer
  • JAH Eekhof
  • A Knuistingh Neven
  1. 1.

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