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Langetermijneffectiviteit van gecombineerde behandeling bij ambulante depressieve patiënten

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Tijdschrift voor Psychotherapie

Abstract

Als vervolg op onze eerdere studie naar het effect van gecombineerde therapie versus farmacotherapie bij ambulante depressieve patiënten in de acute fase presenteren we in dit onderzoek resultaten van gecombineerde therapie in de continuatiefase (een half jaar tot een jaar na de start van de behandeling) en follow-upfase (een tot twee jaar na de start van behandeling). De gecombineerde behandeling bestond uit farmacotherapie in combinatie met Kortdurende Psychoanalytische Steungevende Psychotherapie (KPSP). Bij een groep van 29 patiënten die na de acute behandeling van een half jaar hersteld waren, is op verschillende meetmomenten onderzocht of zich een terugval in de continuatiefase of een nieuwe episode in de follow-upfase voordeed. Conclusie is dat het terugvalpercentage in de continuatiefase hoog is in vergelijking met andere internationale onderzoeken, maar dat dit ruimschoots gecompenseerd wordt door bemoedigende resultaten in de follow-upfase. Verder blijken vrouwen in de continuatiefase significant vaker terug te vallen dan mannen.

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Authors and Affiliations

  1. www.psychotherapie.bsl.nl

    J. Dekker, P. J. Molenaar & F. de Jonghe

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  1. J. Dekker
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  3. F. de Jonghe
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Additional information

Long-term efficacy of Regular therapy in ambulatory depressive patients

As a follow-up to our previous study on the effects of combining psychotherapy and antidepressants in the treatment of depression in ambulatory patients in the acute phase, we now focused on the effects of Regular therapy in the continuation phase (six months until one year after the start of the treatment) and follow-up phase (one year until two years after the start of the treatment). The Regular treatment consisted of pharmacotherapy and Short-term Psychodynamic Supportive Psychotherapy. The depressive symptoms of 29 recovered patients were assessed at several moments to determine whether or not a relapse or recurrence had occurred. For the continuation phase we found that women show a significantly higher relapse rate than men and that the relapse rate is high in comparison with other studies. However, the results for the follow-up phase are much more satisfactory: not one of the patients suffered a new depressive episode.

J. Dekker en P.J. Molenaar zijn beiden als psycholoog werkzaam op de onderzoeksafdeling van Mentrum, Geestelijke Gezondheidszorg te Amsterdam.

Correspondentieadres: J. Dekker, Mentrum, Klaprozenweg 111, 1033 NN Amsterdam.

F. de Jonghe is als psychiater werkzaam bij Mentrum, Centrum voor Geestelijke Gezondheidszorg te Amsterdam, en is als hoogleraar verbonden aan het Academisch Medisch Centrum te Amsterdam.

Dit onderzoek is uitgevoerd door de Mentrum Depressie Research Groep en mede tot stand gekomen door een stipendium van Eli Lilly Nederland.

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Dekker, J., Molenaar, P.J. & de Jonghe, F. Langetermijneffectiviteit van gecombineerde behandeling bij ambulante depressieve patiënten. PSIE 29, 188–194 (2003). https://doi.org/10.1007/BF03062025

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