Synthesis of naturally occurring partial methyl ethers of myricetin

  • P. N. Sarma
  • G. Srimannarayana
  • N. V. Subba Rao


The synthesis of combretol, annulatin, and europetin—naturally occurring partial methyl ethers of myricetin—is described. Condensation of 2, 4, 6-trihydroxy-ω-methoxyacetophenone with tri-O-methyl galloyl chloride or tri-O-benzyl galloyl chloride furnished the appropriate 3-methoxyflavones, which by a series of reactions furnished the natural myricetin derivatives.


Flavonol Myricetin Potassium Carbonate Anhydrous Potassium Carbonate Dimethyl Sulphate 
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Copyright information

© Indian Academy of Sciences 1974

Authors and Affiliations

  • P. N. Sarma
    • 1
  • G. Srimannarayana
    • 1
  • N. V. Subba Rao
    • 1
  1. 1.Department of ChemistryOsmania UniversityHyderabad

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