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Canadian Anaesthetists’ Society Journal

, Volume 9, Issue 4, pp 319–324 | Cite as

Methoxyflurane

  • J. W. R. McIntyre
  • E. A. Gain
Article

Conclusion

Methoxyflurane is non-inflammable and non-explosive at room temperature, comparable with soda lime, and can be used for general anaesthesia in a vaporizer of simple design. It can be administered most economically in a closed circuit, and the vaporizer can be used safely within the circle. The drug is satisfactory under almost all circumstances but Its slow absorption, respiratory depressant effect, and odour make it unsuitable for a minority of cases. It provides marked analgesia, good muscular relaxation, and a remarkably low incidence of vomiting. With the exception of depression of respiration, and incompatibility with epinephrine, this agent exhibits all of the advantages and none of the disadvantages of diethyl ether with an even greater margin of protection from overdose.

Keywords

Halothane Methoxyflurane Flurane Respiratory Depressant Effect Cent Halothane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

Le méthoxyflurane est non inflammable, non explosif à la température de la salle, utilisable avec la chaux sodée et on peut s’en servir comme anesthesique général en employant un vaporisateur ordinaire. On peut l’employer très économiquement dans un circuit fermé et le vaporisateur peut être placé en toute sécurité dans le circuit. Ce produit donne satisfaction dans presque toutes les circonstances, mais son absorption lente, son effet dépresseur de la respiration et son odeur le rendent peu pratique dans un petit nombre de cas. Il produit une analgésie marquée, un bon relâchement muscu-laire et très peu de vomissements. A part ses effets dépresseurs sur la respiration et son incompatibilité avec l’épinéphrine, cet agent anesthésique présente tous les avantages et aucun des désavantages de l’éther éthylique et possède contre le surdosage, une marge de sécurité encore plus grande que celle de l’éther.

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Copyright information

© Canadian Anesthesiologists 1962

Authors and Affiliations

  • J. W. R. McIntyre
    • 1
  • E. A. Gain
    • 1
  1. 1.Department of AnaesthesiaUniversity of Alberta HospitalEdmonton

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