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Canadian Journal of Anaesthesia

, Volume 47, Issue 9, pp 910–913 | Cite as

Patient anxiety scores after low-dose ketamine or fentanyl for epidural catheter placement

  • Akiyoshi Oda
  • Hiroki Iida
  • Shuji DohiEmail author
Brief Report

Abstract

Purpose: To compare the effect of low-dose ketamine with that of low-dose fentanyl on patient anxiety during the identification of the epidural space and catheterization.

Methods: Sixty patients were randomly assigned to one of three groups: saline group (n=20), saline 2 ml; ketamine group (n=20), 5 mg ketamine; or fentanyl group (n=20), 50µg fentanyl. Each drug was administered intravenously (iv) five to ten minutes before the epidural procedures began. After epidural catheter placement had been accomplished, anxiety and pain were rated using a visual analog scale.

Results: The anxiety scores given for ketamine (20.2±18.5, mean ± SD) and fentanyl (24.6±20.3) were similar, and both were lower than that for saline (44.1±32.7) (P=0.0034 and 0.0153vs saline group, respectively). Pain scores were similar for all three groups. A decrease in hemoglobin oxygen saturation during the procedure was only observed in the fentanyl group, and two patients in fentanyl group had SpO2<90%.

Conclusion: Ketamine, 5 mgiv, is as effective as 50µg fentanyl,iv, in alleviating patient anxiety and in providing adequate sedation during the procedures necessary for epidural catheter placement, without inducing severe complications.

Keywords

Fentanyl Ketamine Saline Group Anxiety Score Patient Anxiety 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

Objectif: Comparer l’effet d’une faible dose de kétamine avec celui d’une faible dose de fentanyl sur l’axiété du patient pendant l’identification de l’espace péridurale et la pose d’un cathéter.

Méthode: Soixante patients ont été répartis au hasard en trois groupes et ont reçu: 2 ml de solution saline (n=20) ou 5 mg de kétamine (n=20) ou 50µg de fentanyl. Cinq à dix minutes avant le début des manœuvres péridurales, on a procédé à l’administration intraveineuse (iv) de chacun des médicaments. Une fois le cathéter installé, on a mesuré l’anxiété de la douleur au moyen de l’échelle visuelle analogique.

Résultats: Les patients qui ont reçu de la kétamine (20,2±18,5 moyenne±écart type) et du fentanyl (24,6±20,3) ont présenté des scores dŕsanxiété similaires, mais plus bas que chez ceux qui ont reçu la solution salée (44,1±32,7) (P=0,0034 et 0,0153vs la solution salée, respectivement). Les scores de douleur n’ont pas présenté de différence intergroupe. Pendant l’intervention, une baisse de la saturation de l’hémoglobine en oxygène a été observée seulement chez les patients qui ont eu du fentanyl. Deux de ces patients montraient une SpO2<90 %.

Conclusion: L’effet de 5 mg de kétamineiv est comparable à celui de 50µg de fentanyliv pour soulager l’anxiété et fournir une sédation adéquate pendant les manœuvres nécessaires à la mise en place d’un cathéter péridural, et ce, sans provoquer de complications importantes.

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Copyright information

© Canadian Anesthesiologists 2000

Authors and Affiliations

  1. 1.From the Department of Anesthesiolgoy and Critical Care MedicineGifu University School of MedicineGifu City, GifuJapan

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