Canadian Journal of Anaesthesia

, Volume 36, Issue 2, pp 145–148 | Cite as

Nitrous oxide does not increase nausea and vomiting following gynaecological laparoscopy

  • Jaromir Hovorka
  • Kari Korttila
  • Olli Erkola


The effect of three different anaesthetic techniques on the incidence and severity of postoperative emesis (nausea, retching and vomiting) was studied in 150 patients undergoing gynaecological laparoscopy. Patients were anaesthetized with isoflurane in nitrous oxide and oxygen (Group A), enflurane in nitrous oxide and oxygen (Group B) or with isoflurane in air and oxygen (Group C). Groups had been predetermined by date of birth. During the first 24 hours after the operation no difference was found at any time in the incidence or severity of emesis among the groups. The overall incidence of emesis during the first 24 hours postoperatively was 54, 48 and 52 per cent, in groups A, B and C, respectively. It is concluded that nitrous oxide does not increase the incidence of emesis after isoflurane anaesthesia and that isoflurane and enflurane anaesthesia are associated with similar incidences of nausea and vomiting after gynaecological laparoscopy.

Key words

ANAESTHETICS GASES: nitrOUS Oxide ANAESTHETICS volatile: enflurane isoflurane complications:nausea and vomiting vomiting: nausea 


ľeffet de trois différentes techniques anesthésiques sur ľincidence et la sévérité du vomissement postopératoire (nausées, haut-le-cour et vomissements) a été étudié chez 150 patientes devant subir une laparoscopie pour opérations gynécologiques. Les patientes furent anesthésiées avec isoflurane, protoxyde ďazote et oxygène (Groupe A), enflurane, protoxyde ďazote et oxygène (Groupe B) ou avec isoflurane, air et oxygène (Groupe C). Les groupes ont été prédéterminés par la date de naissance. Durant les premières 24 heures postop aucune différence ne fut mentionnée en aucun temps sur ľincidence ou la sévérité des vomissements entre les groupes. ľincidence totale des vomissements durant les premières 24 heures postopératoires était de 54, 48 et 52 pour cent dans les groupes A, B et C respectivement. On conclut que le protoxyde ďazote n’augmente pas ľincidence des vomissements après ľanesthésie à V isoflurane et que ľanesthésie à ľisoflurane et ľnflurane est associée avec une incidence identique de nausées et vomissements après laparoscopie pour opération gynécologique.


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Copyright information

© Canadian Anesthesiologists 1989

Authors and Affiliations

  • Jaromir Hovorka
    • 1
    • 2
  • Kari Korttila
    • 1
  • Olli Erkola
    • 1
  1. 1.Department of AnaesthesiaWomen’s Clinics, Helsinki University Central HospitalHelsinkiFinland
  2. 2.Department of AnaesthesiaWomen’s Clinics, Helsinki University Central HospitalHelsinkiFinland

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