Canadian Journal of Anaesthesia

, Volume 39, Issue 2, pp 151–154 | Cite as

Ineffectiveness of acupuncture and droperidol in preventing vomiting following strabismus repair in children

  • S. M. Yentis
  • B. Bissonnette
Reports of Investigation

Abstract

The antiemetic effects and side-effects of P6 acupuncture and droperidol pre-treatment were evaluated in a randomized, patient- and observer-blinded study. Ninety unpremedicated children of ASA physical status I or II undergoing outpatient strabismus repair, and aged over one year, were studied. All patients received intravenous thiopentone 5 mg · kg−1, atropine 0.02 mg · kg−1 and succinylcholine 1.5 mg · kg−1, and the trachea was intubated. Patients then received either intravenous droperidol 0.075 mg · kg−1, droperidol plus five minutes’ P6 acupuncture, or acupuncture alone. Anaesthesia was maintained with nitrous oxide 66% and halothane 1.5–2.0% in oxygen with spontaneous ventilation. There was no difference in the incidence of vomiting in the droperidol group (17% before discharge from hospital and 41% up to 48 hours after discharge), combined treatment group (17% and 34% respectively) and acupuncture group (27% and 45% respectively). Corresponding figures for the incidence of vomiting before discharge were 17%, 17% and 27% respectively; these values were also not different. The incidence of restlessness was significantly greater in children receiving droperidol (63%) or both treatments (67%) than in those receiving acupuncture alone (30%; P = 0.007). P6 acupuncture and droperidol are equally ineffective in preventing vomiting within 48 hours of paediatric strabismus repair. Droperidol is associated with increased incidence of postoperative restlessness.

Key words

anaesthesia: paediatric anaesthetic techniques: acupuncture surgery: ophthalmic, paediatric vomiting: droperidol, incidence 

Résumé

Les effets antiémétiques et les effets secondaires de l’acupuncture P6 et d’un prétraitement au dropéridol ont été évalués lors d’une étude à double insu et au hasard. Quatre-vingt-dix enfants non prémédiqués, classés ASA I ou II, devant subir une chirurgie pour strabisme en cas d’un jour et ågés de plus d’un an, ont été étudiés. Tous les patients ont reçu du thiopental 5 mg · kg−1, de l’atropine 0,02 mg · kg−1 et de la succinylcholine 1,5 mg · kg−1 iv et la trachée a été intubée. Par la suite, les patients ont reçus soit une dose intraveineuse de dropéridol de 0,075 mg · kg−1, soit du dropéridol et 5 minutes d’acupuncture P6, ou seulement de l’acupuncture. L’anesthésie était maintenue à l’aide de protoxyde d’azote 66% et d’halothane 1,5 à 2% avec oxygène, sous ventilation spontanée. Il n’y avait aucune différence dans l’incidence de vomissements chez le groupe dropéridol (17% avant le congé de l’hôpital et 41% jusqu’à 48 heures après le congé), le groupe avec traitement combiné (17% et 34% respectivement) et le groupe acupuncture (27% et 45% respectivement). Les figures correspondantes pour l’incidence de vomissements avant le congé étaient de 17%, 17% et 27% respectivement; ces valeurs n’étaient également pas différentes. L’incidence d’agitation était significativement plus élevée chez les enfants recevant du dropéridol (60%) ou les deux traitements (67%) que chez ceux recevant seulement l’acupuncture (30%; P = 0,007). L’acupuncture P6 et le dropéridol sont tous les deux inefficaces dans la prévention des vomissements, dans les premières 48 heures d’une chirurgie pédiâtrique pour le strabisme. Le dropéridol est associé à une incidence augmentée d’agitation postopératoire.

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Copyright information

© Canadian Anesthesiologists 1992

Authors and Affiliations

  • S. M. Yentis
    • 1
  • B. Bissonnette
    • 1
  1. 1.Department of Anaesthesia, The Hospital for Sick Children and the Research InstituteUniversity of TorontoOntarioCanada

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