Canadian Anaesthetists’ Society Journal

, Volume 26, Issue 4, pp 260–262 | Cite as

Phaeochromocytoma and postoperative hypoglycaemia

  • René Martin
  • Bruno St-Pierre
  • Ouida-Ramon Moliner


A case of hypoglycaemia following the removal of a phaeochromocytoma is reported and the mechanisms that influence the blood sugar before and after the removal of that tumour are discussed.


Blood Sugar Sodium Nitroprusside Phentolamine Phaeochromocytoma Vanillylmandelic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Nous rapportons un cas ďhypoglycémie post-opératoire suivant ľexcision ďun phéo-chromocytome, et nous discutons les mécanismes physiologiques qui influencent la glycémie avant et après ľexcision de cette tumeur.


  1. 1.
    Thorn, G.W., Adams, R.D., Braunwald, E., IsselBACHER, K.J. &Petersdorf, R.G. Principles of internal medicine 8 ed., McGraw-Hill. New York. 560 (1977).Google Scholar
  2. 2.
    Suore, Y., Beck-Girandon, B., Pouget-Abadie, J.F.,et al. Le diabète du phéo-chromocytome. Sem. Hôp. Paris52: 1893–1902 (1976).Google Scholar
  3. 3.
    Perry, L.B. &Gould, A.B., {jrJr.} The anesthetic management of pheochromocytoma: effect of preoperative adrenergic blocking drugs. Anesth. Analg. (deve)51: 36 (1972).Google Scholar
  4. 4.
    Allen, C.T.B. &Imrie, D. Hypoglycemia as a complication of removal of a pheochromocytoma. Can. Med. Ass. J.116: 363–364 (1977).PubMedGoogle Scholar
  5. 5.
    Wilkins. G.E., Schmidt, N. &Doll, W.A. Hypoglycemia following excision of pheochromocytoma. Can. Med. Ass. J.116: 367–368 (1977).PubMedGoogle Scholar
  6. 6.
    Porte, D., {jrJr.} A receptor mechanism for the inhibition of insulin release by epinephrine in man. J. Clin. Invest.46: 86 (1967).PubMedGoogle Scholar
  7. 7.
    Cerasi, E., Effendic, S. &Luft, R. Role of adrenergic receptors in glucose-induced insulin secretion in man. Lancet2: 301 (1969).PubMedCrossRefGoogle Scholar
  8. 8.
    Spergel, G., Bleicher, S.H. &Ertel, N.H. Carbohydrate and fat metabolism in patients with pheochromocytoma. N. Engl. J. Med.278: 803 (1968).PubMedGoogle Scholar
  9. 9.
    Randle, P.H., Garland. P.B., Hales, C.N.,et al. Glucose fatty-acid cycle: its role in insulin sensitivity and metabolic disturbance of diabetes mellitus. Lancet1: 785 (1963).PubMedCrossRefGoogle Scholar
  10. 10.
    Schalch, D.S. &Kipnis, D.M. Abnormalities in carbohydrate tolerance associated with elevated plasma nonesferified fatty acids. J. Clin. Invest.44: 2010 (1965).PubMedCrossRefGoogle Scholar
  11. 11.
    Goldenberg, I.S., Hayes, M.A. &Greene, N.M. Endocrine response during operative procedures. Ann. Surg.150: 190 (1959).CrossRefGoogle Scholar
  12. 12.
    Lindseth, R.E. Postoperative glucose metabolism in diabetic and non-diabetic patients. Arch. Surg.105: 741 (1972).PubMedGoogle Scholar
  13. 13.
    Cooper, C.E. &Nelson, D.H. ACTH levels in plasma in preoperative and surgically stressed patients. J.Clin. Invest.41: 1599 (1962).PubMedCrossRefGoogle Scholar
  14. 14.
    Greene, N.M. &Goldenberg, I.S. The effect of anesthesia on thyroid activity in humans. Anesthesiology20: 125 (1959).CrossRefGoogle Scholar
  15. 15.
    Porte, D., {jrJr.},Graber, A., Kuzuya, T.,et al. The effect of epinephrine on immunoreactive insulin levels in man. J. Clin. Invest.45: 228 (1966).PubMedCrossRefGoogle Scholar
  16. 16.
    Shand, D.G. Propanolol. N. Engl. J. Med.293: 280 (1975).PubMedGoogle Scholar
  17. 17.
    Skinner, D.J. Uses of propanolol. N. Engl. J. Med.293: 1205 (1975).CrossRefGoogle Scholar
  18. 18.
    Lloyd-Mostyn, R.H. &Oram. S. Modification by propanolol of cardio-vascular effects of induced hypoglycemia. Lancet2: 1213–1215 (1975).CrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1979

Authors and Affiliations

  • René Martin
    • 1
  • Bruno St-Pierre
    • 1
  • Ouida-Ramon Moliner
    • 1
  1. 1.Department of AnesthesiaUniversity of Sherbrooke, Centre Hospitalier Universitaire of SherbrookeSherbrookeCanada

Personalised recommendations