Canadian Anaesthetists’ Society Journal

, Volume 26, Issue 6, pp 482–483

The effect of lidocaine on succinylcholine-induced rise in intraocular pressure

  • R. Brian Smith
  • Maciej Babinski
  • Napoleon Leano


The effect of lidocaine on the increase of intraocular pressure induced by succinylcholine was studied in patients 6 to 85 years of age. Three groups of patients were studied. One group of eight patients received lidocaine 1 mg·kg-1 before succinylcholine and a control group of ten patients did not have lidocaine. Anaesthesia was induced with thiopentone 5 mg·kg-1 and maintained with nitrous oxide 50 per cent with oxygen and halothane 1.0-1.5 per cent. The tracheae of all patients were intubated.

Lidocaine in doses of 1.0 to 2.0 mg·kg-1 did not prevent transient rise in intraocular pressure following administration of succinylcholine and tracheal intubation.


Ľétude porte sur trois groupes de patients et évalue ľeffet de ľinjection de lidocaíne sur ľaugmentation de la tension intraoculaire dgmentationclenchgmentatione par la succinylcholine. Un premier groupe de huit patients a reçu lidocaíne 1 mg·kg-1 avant la succinylcholine, un deuxième de dix patients, lidocaíne 2 mg·kg1 avant la succinylcholine, et un troisième de dix patients n’a reçu que la succinylcholine et a servi de contrôle. Ľanesthísie fut réalisée avec du thiopental 5 mgékg-1 suivi de protoxyde ďazote-oxygène à 50 pour cent avec halothane 1.0 à 1.5 pour cent. Tous les patients furent intubés.

La lidocaíne aux doses de 1.0 à 2.0 mg·kg-1 n’a pas empêché ľaugmentation transitoire de la tension intraoculaire provoquée par ľadministration de succinylcholine et ľintubation trachéale.


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Copyright information

© Canadian Anesthesiologists 1979

Authors and Affiliations

  • R. Brian Smith
    • 1
  • Maciej Babinski
    • 1
  • Napoleon Leano
    • 1
  1. 1.Department of AnesthesiologyUniversity of Texas, Health Science CenterSan AntonioU.S.A.

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