Canadian Anaesthetists’ Society Journal

, Volume 26, Issue 6, pp 482–483

The effect of lidocaine on succinylcholine-induced rise in intraocular pressure

  • R. Brian Smith
  • Maciej Babinski
  • Napoleon Leano
Article

Summary

The effect of lidocaine on the increase of intraocular pressure induced by succinylcholine was studied in patients 6 to 85 years of age. Three groups of patients were studied. One group of eight patients received lidocaine 1 mg·kg-1 before succinylcholine and a control group of ten patients did not have lidocaine. Anaesthesia was induced with thiopentone 5 mg·kg-1 and maintained with nitrous oxide 50 per cent with oxygen and halothane 1.0-1.5 per cent. The tracheae of all patients were intubated.

Lidocaine in doses of 1.0 to 2.0 mg·kg-1 did not prevent transient rise in intraocular pressure following administration of succinylcholine and tracheal intubation.

Résumé

Ľétude porte sur trois groupes de patients et évalue ľeffet de ľinjection de lidocaíne sur ľaugmentation de la tension intraoculaire dgmentationclenchgmentatione par la succinylcholine. Un premier groupe de huit patients a reçu lidocaíne 1 mg·kg-1 avant la succinylcholine, un deuxième de dix patients, lidocaíne 2 mg·kg1 avant la succinylcholine, et un troisième de dix patients n’a reçu que la succinylcholine et a servi de contrôle. Ľanesthísie fut réalisée avec du thiopental 5 mgékg-1 suivi de protoxyde ďazote-oxygène à 50 pour cent avec halothane 1.0 à 1.5 pour cent. Tous les patients furent intubés.

La lidocaíne aux doses de 1.0 à 2.0 mg·kg-1 n’a pas empêché ľaugmentation transitoire de la tension intraoculaire provoquée par ľadministration de succinylcholine et ľintubation trachéale.

References

  1. 1.
    Usubiaga, J.E., Wlkinski, J.A., Usubiaga, L.E. &Molina, F. Intravenous lidocaine in the prevention of postoperative muscle pain caused by succinylcholine administration. Anes. Anal.46: 225, (1967).Google Scholar
  2. 2.
    Sharma, H.R. Role of xylocaine in the prevention of postsuxamethonium muscle pain. Abstract F8/95 from the World Federation of Anesthesiologists. Japan, 1972.Google Scholar
  3. 3.
    Lincoff, H.A., Ellis, C.H., DeVoe, A.G., DeBeer, E.J., Impastanto, D.J., Berg, S., Orkin, L. &Magda, J. The effect of succinylcholine on intraocular pressure. Amer. J. Ophthal.40: 501 (1955).PubMedGoogle Scholar
  4. 4.
    Wynands, J.E. &Crowell, D.E. Intraocular tension in association with succinylcholine and endotracheal intubation: a preliminary report. Canad. Anaesth.Soc. J.7: 39(1960).PubMedGoogle Scholar
  5. 5.
    Taylor, T.H., Mulcahy, M. &Nightingale, D.A. Suxamethonium chloride in intraocular surgery. Brit. J. Anaesth.40: 113 (1968).PubMedCrossRefGoogle Scholar
  6. 6.
    Pandey, K., Badola, R.P. &Kumar, S. Time course of intraocular hypertension produced by suxamethonium. Brit. J. Anaesth.44: 191 (1972).PubMedCrossRefGoogle Scholar
  7. 7.
    Sobel, A.M. Hexafluorenium, succinylcholine, and intraocular tension. Anes. Anal.41: 399(1962).CrossRefGoogle Scholar
  8. 8.
    Miller, R.D., Walter, L.W. &Hickey, R.F. Inhibition of succinylcholine-induced increased intraocular pressure by non-depolarizing muscle relaxants. Anesthesiology29: 123(1968).PubMedCrossRefGoogle Scholar
  9. 9.
    Carballo, A.S. Succinylcholine and acetazolamide (Diamox) in anaesthesia for ocular surgery. Can. Anaes. Soc. J.12: 486(1965).CrossRefGoogle Scholar
  10. 10.
    Craythorne, N.W.B., Rottenstein, H.S. &Dripps, R.D. The effect of succinylcholine on the intraocular pressure in adults, infants and children during general anesthesia. Anesthesiology21: 59 (1960).PubMedCrossRefGoogle Scholar
  11. 11.
    Miller, R.D. &Walter, L.W. Inhibition of succinylcholine induced increased intragastric pressure by non-depolarizing muscle relaxants and lidocaine. Anesthesiology34: 185(1971).PubMedGoogle Scholar
  12. 12.
    Davanger, M. The difference in ocular pressure in the two eyes of the same person. Acta Ophthalmologica43: 299 (1965).PubMedCrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1979

Authors and Affiliations

  • R. Brian Smith
    • 1
  • Maciej Babinski
    • 1
  • Napoleon Leano
    • 1
  1. 1.Department of AnesthesiologyUniversity of Texas, Health Science CenterSan AntonioU.S.A.

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