Canadian Journal of Anaesthesia

, Volume 36, Issue 5, pp 530–532 | Cite as

Malignant hyperthermia and the clean machine

  • Terrence T. McGraw
  • Thomas P. Keon
Reports of Investigation


Following use with halothane, ten anaesthestic machines were sampled using infrared analysis for halothane contamination. Baseline measurements of halothane were made in the room and at the machine’s common gas outlet. Five per cent halothane with four litres per minute oxygen flow was delivered for ten minutes into a scavenged breathing circuit. Halothane was then discontinued, an oxygen flow rate of 12 litres per minute was begun, and continuous measurements were made until the halothane concentration became undetectable. Baseline measurements of the rooms and anaesthestic machines ranged from 0 to 0.8 parts per million. Following the oxygen flow, the halothane concentration decreased to undetectable levels within six minutes in all ten machines.

Key words

Anaesthetics, volatile: halothane Equipment: anaesthetic machines Hyperthermia: malignant 


Nous avons analysé à l’infra-rouge, l’air ambiant et les gaz à la sortie de dix appareils d’anesthisie. Les mesures révelaient des concentrations d’halothane variant de 0 à 0.8 parties par million. Nous avons ensuite instilli dans un systéme respiratoire muni d’un dispositif anti-pollution, cinq pour cent d’halothane avec quatre litres min−1 d’oxygéne pendant dix minutes. Nous avons par la suite mesure continuellement le niveau d’halothane pendant le lavage du systeme avec 12 litre min−1 d’oxygéne. Avec les dix appareils, en moins de six minutes de lavage, la concentration d’halothane était passée sous le seuil de detection.


  1. 1.
    Relton JE. Anesthesia for elective surgery in patients susceptible to malignant hyperthermia. Int Anesthesiol Clin 1979; 17: 142–51.Google Scholar
  2. 2.
    Eger El, Larson P, Severinghaus J. The solubility of halothane in rubber, soda lime, and various plastics. Anesthesiology 1962; 23: 356–9.PubMedCrossRefGoogle Scholar
  3. 3.
    Beebe JJ, Sessler DI. Preparation of anesthesia machines for patients susceptible to malignant hyperthermia. Anesthesiology 1988; 69: 395–400.PubMedCrossRefGoogle Scholar
  4. 4.
    Technical Bulletinf or Malignant Hyperthermia. Anesthesia Technical Bulletin No. 1. the American Society of Anesthesiologists Newsletter, November 1982.Google Scholar
  5. 5.
    Samulksa HM, Samala R, Noble WH. Unintended exposure to halothane in surgical patients: halothane washout studies. Can Anaesth Soc J 1972; 19: 35–41.CrossRefGoogle Scholar
  6. 6.
    National Institute of Occupational Safety and Health: A Recommended Standard for Occupation Exposure to Waste Anesthetic Gases and Vapors. Washington, DC, US Government Printing Office, 1977, ppl-3.Google Scholar
  7. 7.
    Ritchie PA, Cheshire MA, Pearce NH. Decontamination of halothane from anaesthetic machines achieved by continuous flushing with oxygen. Br J Anaesth 1988; 60: 859–63.PubMedCrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1989

Authors and Affiliations

  • Terrence T. McGraw
    • 1
    • 2
  • Thomas P. Keon
    • 1
    • 2
  1. 1.Department of AnaesthesiaUniversity of PennsylvaniaPhiladelphia
  2. 2.Department of Anesthesia and Critical CareChildren’s Hospital of PhiladelphiaPhiladelphia

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