Irish Journal of Medical Science

, Volume 143, Issue 1, pp 145–154 | Cite as

Characteristics of methicillin resistant Staphylococcus aureus

  • Rosemary Hone
  • C. T. Keane


THE frequency of methicillin resistant Staphylococcus aureus isolated from pathological material from eight Dublin hospitals between April, 1971 and April, 1972 was 5.4 per cent. This frequency justifies their routine detection.

Characteristics of 90 methicillin resistant strains are examined. They include antibiotic sensitivity and sensitivity to metal ions, phage types, lipolytic activity, heterogeneity and temperature studies.


Staphylococcus Aureus Methicillin Methicillin Resistant Staphylococcus Aureus Lipolytic Activity IRISH Journal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Al Salihy, S. M. and James, A. M. 1972. Loss of methicillin-resistance from resistant strains of Staphylococcus aureus. Lancet ii, 331.Google Scholar
  2. Annear, D. I. 1968. The effect of temperature on resistance of Staphylococcus aureus to methicillin and some other antibiotics. Med. J. Aust. 1, 444.PubMedGoogle Scholar
  3. Barber, Mary, Dutton, A. A. C., Beard, M. A., Elmes, P. C. and Williams, R. 1960. Reversal of antibiotic resistance in hospital staphylococcal infection. Br. med. J. i, 11.Google Scholar
  4. Marber, Mary 1964. Naturally occurring methicillin resistant staphylococci. J. Gen. Microbiol. 35, 183.Google Scholar
  5. Barrett, F. F., McGehee, R. F. and Finland, M. 1968. Methicillin resistant Staphylococcus aureus at Boston City Hospital. New Engl. J. Med. 279, 441.PubMedGoogle Scholar
  6. Benner, E. J. and Kayser, F. H. 1968. Clinical significance of methicillin resistant Staphylococcus aureus. Lancet, ii, 741.Google Scholar
  7. Blair, J. E. and Williams, R. E. O. 1961. Phage typing of staphylococci. Bull. Wld. Hlth. Org. 24, 771.Google Scholar
  8. Chabbert, Y. A., Budens, J. G., Acar, T. F. and Gerbaud, G. R. 1965. La resistance naturelle des Staphylocoques a La Methicillins et l'Oxacillins. Revue fr. Etud. Clin. Biol. 10, 495.Google Scholar
  9. Churcher, Gillian M. 1968. A screening test for the detection of methicillin resistant staphylococci. J. Clin. Path. 21, 213.PubMedCrossRefGoogle Scholar
  10. Cohen, S. and Sweeney, H. M. 1970. Transduction of methicillin resistance in Staphylococcus aureus dependent on an unusual specificity of the recipient strain. J. Bacteriol. 104, 1158.PubMedGoogle Scholar
  11. Cowan, S. T. and Steel, K. J. 1970. Identification of Medical Bacteria. Cambridge University Press. pp. 153–154.Google Scholar
  12. Darrell, J. H., Garrod, L. P. and Waterworth, Pamela M. 1968. Trimethoprim: laboratory and clinical studies. J. Clin. Path. 21, 202.PubMedCrossRefGoogle Scholar
  13. Dornbush, K., Hallender, H. O. and Lofquist, F. 1969. Extra-chromosomal control of methicillin resistance and toxin production in Staphylococcus aureus. J. Bacteriol. 98, 351.Google Scholar
  14. Dyke, K. G. H., Parker, M. T. and Richmond, M. H. 1970. Penicillinase production and metal ion resistance in Staphylococcus aureus cultures isolated from hospital patients. J. Med. Microbiol. 3, 125.PubMedGoogle Scholar
  15. Garrod, L. P. and Waterworth, Pamela M. 1971. A study of antibiotic sensitivity testing with proposals for simple uniform methods. J. Clin. Path. 24, 779.PubMedCrossRefGoogle Scholar
  16. Goldie, D. J., Alder, V. G. and Gillespie, W. A. 1971. Changes in the drug resistance of Staphylococcus aureus in a non hospital population during a 20-year period. J. Clin. Path. 24, 44.PubMedCrossRefGoogle Scholar
  17. Green, Susan M. 1962. Mercury sensitivity of staphylococci. J. Clin. Path. 15, 249.PubMedCrossRefGoogle Scholar
  18. Grubb, W. B. and Annear, D. I. 1972. Spontaneous loss of methicillin resistance in Staphylococcus aureus at room temperature. Lancet ii, 1257.CrossRefGoogle Scholar
  19. Hewitt, J. H., Coe, A. W. and Parker, M. T. 1969. The detection of methicillin resistance in Staphylococcus aureus. J. Med. Microbiol. 2, 443.PubMedGoogle Scholar
  20. Jevons, M. Patricia. 1961. Celbenin-resistant staphylococci. Br. med. J. i, 124.Google Scholar
  21. Jessen, Q. Faber, V., Rosendal, K. and Ericsen, K. R. 1959. Some properties of Staphylococcus aureus possibly related to pathogenicity. Acta. Path. Microbiol. Scand. 47, 316.PubMedGoogle Scholar
  22. Jessen, O., Rosendal, K., Bulow, P., Faber, V. and Ericksen, M. R. 1969. Changing Staphylococci and Staphylococcal infections. New Engl. J. Med. 281, 627.PubMedCrossRefGoogle Scholar
  23. May, J. R. and Davies, J. 1972. Resistance of haemophilus influenzae to trimethoprim. Br. med. J. 3, 376.PubMedCrossRefGoogle Scholar
  24. Moorhouse, Ellen C. and Farrell, Wendy. 1971. Nasal and intestinal carriage of antibiotic resistant bacteria by patients on admission to hospital. J. Irish. Med. Ass. 64, 571.Google Scholar
  25. Nakhia, L. S. 1972. Resistance of Staphylococcus aureus to sulphamethoxazole and trimethoprim. J. Clin. Path. 25, 708.CrossRefGoogle Scholar
  26. Parker, M. T. and Hewitt, J. H. 1970. Methicillin resistance in Staphylococcus aureus. Lancet i, 800.CrossRefGoogle Scholar
  27. Siboni, K., Poulsen, L. and Digman, E. 1968. The dominance of methicillin resistant staphylococci in a county hospital. Danish Medical Bulletin. 15, 161.PubMedGoogle Scholar
  28. Sierra, G. 1957. A simple method for the detection of lipolytic activity of micro-organisms and some observations on the influence of the contact between cells and fatty substrates. Antonie Leeuwenhoek, J. Microbiol. Serol. 23, 15.Google Scholar

Copyright information

© Springer 1974

Authors and Affiliations

  • Rosemary Hone
    • 1
  • C. T. Keane
    • 1
  1. 1.Central Microbiology LaboratoryAdelaide HospitalDublin 8

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