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Effect of methoxyflurane anaesthesia on thyroid function in man

  • Tsutomu Oyama
  • S. Shibata
  • A. Matsuki
  • T. Kudo
Article

Summary and Conclusion

The effect of methoxyflurane-nitrous-oxide-oxygen anaesthesia on thyroid function was studied in 21 subjects. Neither significant alteration in blood thyroxine (I131-T4) level nor blood triiodothyronine (I131-T3) sponge uptake was noted during anaesthesia. These findings would suggest that methoxyflurane anaesthesia has no significant influence on thyroid activity in man.

Keywords

Thyroxine Triiodothyronine Methoxyflurane Thyroxine Level Thyroid Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

On a recherché Ľeffet de Ľanesthésie au méthoxyflurane-protoxyde ďazoteoxygène sur la fonction thyroïdienne chez 21 sujets. On n’a décelé aucun changement important dans le niveau de thyroxine radioactive (I131-T4) dans le sang, ni dans la triiodothyronine (I131-T3) du sang. Ces observations portent à croire que Ľanesthésie au méthoxyflurane n’a pas ďinfluence importante sur Ľactivité thyroïdienne chex Ľhomme.

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References

  1. 1.
    Oyamta, T. Effects of Anesthesia on Thyroid Function of Rats. Anesthesiology.18: 719 (1957).CrossRefGoogle Scholar
  2. 2.
    Oyama, T. Effects of Diethyl Ether Anesthesia on Thyroid Function of Rats. Endocrinology.65: 56 (1959).PubMedGoogle Scholar
  3. 3.
    Hydovitz, J. D. Effect of Anesthesia and Thyroid Surgery on the Plasma Level of PBI131. J. Clin. Endocr.17: 76 (1956).CrossRefGoogle Scholar
  4. 4.
    Green, N. M. &Goldenberg, I. S. The Effect of Anesthesia on Thyroid Activity in Humans. Anesthesiology.20: 125 (1959).CrossRefGoogle Scholar
  5. 5.
    Johnston, I. D. Endocrine Aspects of the Metabolic Response to Surgical Operation. Ann. Roy. Coll. Surg. England.35: 270 (1964).Google Scholar
  6. 6.
    Fore, W.;Kohler, P.; &Wynn, J. Rapid Redistribution of Serum Thyroxine during Ether Anesthesia. J. Clin. Endocr.26: 821 (1966).PubMedGoogle Scholar
  7. 7.
    Mitchell, M. L. Resin Uptake of Radiothyroxine in Sera from Non-pregnant and Pregnant Women. J. Clin. Endocr.18: 1437 (1958).PubMedGoogle Scholar
  8. 8.
    Oyama, T.;Shibata, S.; &Matsuki, A. Thyroxine Distribution during Ether and Thiopental Anesthesia in Man. Anesth. & Analg.48: 1 (1969).CrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1969

Authors and Affiliations

  • Tsutomu Oyama
    • 1
  • S. Shibata
    • 1
  • A. Matsuki
    • 1
  • T. Kudo
    • 1
  1. 1.Department of AnesthesiologyHirosaki University, School of MedicineHirosakiJapan

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